Join University at Buffalo Department of Pharmaceutical Sciences faculty, staff and alumni at this celebrated quadrennial event.
Program Speaker: Free
Program Attendee: $300
Program Attendee Guest: $75 for attending 1 event dinner or $125 for both
Faculty/Staff: $50
UB Student: $25
Children under 10: Free
Welcome Reception and Dinner*
*Bus transportation will be available to Rich's from the Hyatt Place Buffalo/Amherst departing at 5:45 p.m. Bus will depart from Rich's to return to the Hyatt Place Buffalo/Amherst at approximately 9:15 p.m.
6:00 p.m.
Opening Reception
The Atrium @ Rich's
1 Robert Rich Way
Buffalo, NY 14213
View a map and directions
7:00 p.m.
Opening Remarks
William J. Jusko, PhD
SUNY Distinguished Professor, Department of Pharmaceutical Sciences, University at Buffalo
7:05 p.m.
Dean's Welcome
Gary M. Pollack, PhD
Dean and Professor, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo
7:15 p.m.
Department Highlights
Donald E. Mager, PharmD, PhD
Chair and Professor, Department of Pharmaceutical Sciences, University at Buffalo
After Dinner
Dr. Ho-Leung Fung Tribute
9:15 p.m.
Bus shuttle departs from Rich's to return attendees staying at the Hyatt Place
190 Pharmacy Building, UB South Campus*
*Shuttle transportation will be available for Hyatt Place guests to and from the Pharmacy Building, departing from the hotel at 8:00 a.m. and then departing from the Pharmacy Building at 5:15 p.m.
8:30 a.m.
Registration/Continental Breakfast
9:00 a.m.
Welcome Introduction
William J. Jusko, PhD
SUNY Distinguished Professor, Department of Pharmaceutical Sciences, University at Buffalo
Session 1: Honoring Marilyn Morris: Complexities in Drug Disposition
Chair — Jason A. Sprowl, PhD
Assistant Professor, Department of Pharmaceutical Sciences, University at Buffalo
9:05 a.m.
Marilyn E. Morris: An Astonishing Career
Gayle A. Brazeau, PhD
Professor, Department of Pharmaceutical Sciences, Marshall University
9:15 a.m.
Clinical Pharmacology in New Drug Development
Lisa Benincosa, PhD
Senior Vice President of Clinical Pharmacology Strategy, Allucent
9:45 a.m.
Regulatory science on transporter-mediated drug interactions
Xinning Yang, PhD
Silver Spring, MD
10:15 a.m.
Coffee Break
10:45 a.m.
Role of Hepatic Organic Cation Transporter 1 (OCT1) in Drug-Metabolite Disposition
Bridget L. Morse, PharmD/PhD
Drug Disposition, Eli Lilly & Co.
11:15 a.m.
Experiences in TMDD Modeling of Small Molecules
Guohua An, MD, PhD
Associate Professor, University of Iowa
12:00 p.m.
Lunch/Student Poster Presentations/Group Photo/P-GSA & UB-AAPS Alumni Mentoring Lunch
Session 2: Protein Therapeutics
Chair - Dhaval Shah, PhD
Associate Professor, Department of Pharmaceutical Sciences, University at Buffalo
2:00 p.m.
Overview of the Department of Pharmaceutical Sciences
Donald E. Mager, PharmD, PhD
Chair and Professor, Department of Pharmaceutical Sciences, University at Buffalo
2:15 p.m.
New Strategies to Increase the Safety and Efficacy of Anti-Cancer Antibody Therapies
Joseph P. Balthasar, PhD
David and Jane Chu Endowed Chair in Drug Discovery and Development, Professor of Pharmaceutical Sciences, Director of the Center for Protein Therapeutics, Executive Director of University Research Initiatives, University of Buffalo
2:45 p.m.
Considerations in Clinical Pharmacology Approaches to Support Development of T cell Redirecting Bispecific Antibodies - Harnessing the Power of Mechanistic Modeling
Xiling Jiang, PhD
Silver Spring, MD
3:15 p.m.
Coffee Break
3:45 p.m.
The Posology of Dupilumab in Pediatric Patients
Mohamed Kamal, PharmD, PhD
Senior Director of Clinical Pharmacology, Regeneron
4:15 p.m.
Model-Based Assessment of Anti-FcRn Antibody DDI Potentials
Weirong Wang, PhD
Senior Scientific Director, Janssen R&D, Johnson & Johnson
6:00 - 9:00 p.m.
Symposium Reception*
Burchfield Penney Art Center
1300 Elmwood Avenue
Buffalo, NY 14222
View a map and directions
*Bus transportation will be available to the Burchfield Penney from the Hyatt Place and UB. Shuttle will depart from the Hyatt Place at 6:00 p.m. Shuttles will depart from the Burchfield Penney at approximately 9:15 p.m
190 Pharmacy Building, UB South Campus*
*Shuttle transportation will be available for Hyatt Place guests to and from the Pharmacy Building, departing from the hotel at 8:00 a.m. and then departing from the Pharmacy Building at 5:30 p.m.
8:30 a.m.
Registration/Continental Breakfast
Session 3: Pharmacokinetics, Pharmacodynamics, and Systems Modeling
Chair – Sukyung Woo, PhD
Associate Professor, Department of Pharmaceutical Sciences, University at Buffalo
9:00 a.m.
Systems Modeling in Model-Informed Drug Development – Case Studies
Holly Kimko, PhD
Global Head of Systems Medicine, AstraZeneca
9:45 a.m.
Model-Based Dose Justification Strategies for T-Cell-Redirecting Bispecific Antibodies in Multiple Myeloma
Mahesh Samtani, PhD
Senior Director, Janssen Pharmaceuticals
10:15 a.m.
Coffee Break
10:45 a.m.
Clinical Pharmacology Applications in Cystic Fibrosis
Brenda Cirincione, PhD
Vice President, Clinical and Quantitative Pharmacology, Vertex Pharmaceuticals
11:15 a.m.
Integrating Mechanistic and Machine Learning for Optimal Drug Design
Peter Bloomingdale, PhD
Senior Associate Director, Pharmacometrics, Boehringer Ingelheim
12:00 p.m.
Lunch/Poster Presentations
Session 4: Drug Delivery and Drug Development
Chair – Robert M. Straubinger, PhD
Professor, Department of Pharmaceutical Sciences, University at Buffalo
2:00 p.m.
Focused Ultrasound-Mediated CRISPR Delivery for Somatic Genome Editing in the Brain
Sima Lao, PhD
Assistant Professor, Department of Pharmaceutical Sciences, University at Buffalo
2:45 p.m.
A Paradigm Shift in Oncology Drug Design
Brian Booth, PhD
Director, Division of Cancer Pharmacology I, FDA/CDER/OTS/OCP
3:15 p.m.
Coffee Break
3:45 p.m.
Modeling Cellular Kinetics of CAR-T Therapy in Humans
Yanguang Cao, PhD
Associate Professor, Division of Pharmacotherapy and Experimental Therapeutics, University of North Carolina
4:15 p.m.
Multi-omic Strategies to Advance Development of Nanomedicines: Optimizing Dosing Schedules of Topotecan in Aggressive Metastatic Prostate Cancers
Robert D. Arnold, PhD
Professor and Director of Research Development & Support, Drug Discovery & Development, Auburn University
4:45 p.m.
Closing Remarks and Departure
Student Poster Displays
Panasci Atrium
Hyatt Place Buffalo/Amherst
5020 Main Street
Amherst, NY 14226
View a map and directions
Reservations: book online or call 1-888-492-8847
Cost: $179 standard room per night*
*Discounted rate available until June 23, 2023. Indicate you are registering under the Buffalo Pharmaceutics Symposium.
Bus transportation from the Hyatt Place Buffalo/Amherst will be available to the Pharmacy Building.
Sponsorship Questions?
Please contact Leigh Yates, Assistant Dean for Development, at ltyates@buffalo.edu or 716-645‐3432.
Department of Pharmaceutical Sciences
University at Buffalo
445 Pharmacy Building
Buffalo, NY 14214
716-645-2138
Email: mrbewley@buffalo.edu