Active Projects Academic Year 19-20

Award Principal Investigator Award Name Award Type Sponsor Name Award Start Date Award End Date Total Cost
Balthasar, Dr. Joseph Catch and Release Immunotoxins: CAR-Bombs for Cancer Federal National Cancer Institute 07-Dec-2016 30-Nov-2021 $1,816,235.00
Balthasar, Dr. Joseph Center for Protein Therapeutics Nonfederal Multiple Sponsors 01-Sep-2017 31-Aug-2020 $5,024,501.70
Balthasar, Dr. Joseph P. Evaluation of CAR-Bomb strategies for targeted delivery of anti-cancer siRNA Non-federal Center for Protein Therapeutics 1-Sep-19 31-Aug-2020 $100,000.00
Balthasar, Dr. Joseph P. Evaluation of the effects of cell penetrating peptides and endosomal escape peptides on the pharmacokinetics of anti-cancer monoclonal antibodies Non-federal Center for Protein Therapeutics 1-Sep-19 31-Aug-2020 $100,000.00
Balthasar, Dr. Joseph P. Evaluation of the therapeutic selectivity of anti-CEA SN38 antibody-drug conjugates (ADC) and antibody drug fragment complexes (FDC) Non-federal Center for Protein Therapeutics 1-Sep-19 31-Aug-2020 $100,000.00
Balu-Iyer, Dr. Sathy V HL-Development and Pharmacology of novel lipidic rAHF and biotherapeutics Federal National Heart Lung and Blood Institute 05-Oct-2015 31-Dec-2020 1,593,611.46
Balu-Iyer, Dr. Sathy V. Study viable approaches for oral delivery of colon-targeting macromolecules (e.g. targeting TNF for IBD), and understand the gut absorption mechanism following oral delivery Non-federal Center for Protein Therapeutics 1-Sep-19 31-Aug-2020 $100,000.00
Bednarczyk, Dr. Edward M Pharmacy Role in Addressing the Opioid Epidemic Nonfederal Dutchess County Department of Behavioral and Community Health 01-Sep-2019 30-Nov-2019 $6,650.00
Bednarczyk, Dr. Edward M Opioid Prescriber Training Program and Enduring Program Federal Flow Through Health Research Inc 01-Sep-2019 31-Aug-2020 $68,300.00
Bies, Dr. Robert R. Understanding the Relative Contributions of and Critical Enzymes for the Three Pathways for Intracrine Metabolism of Testicular Androgens in Advanced Prostate Cancer Federal US Army Medical Research Acquisition Activity 30-Sep-2016 29-Sep-2020 $276,699.00
Bies, Dr. Robert R. Physiologically-based model of the female reproductive tract: vaginal and intrauterine delivery components- Support New Approaches to Improve Product Manufacturing and Quality Federal US Food and Drug Administration 26-Sep-2018 25-Sep-2022 $888,097.00
Bies, Dr. Robert R. Visiting Scholar: Nikhil Pillai Nonfederal Merck Sharp and Dohme Corporation 10-May-2019 09-May-2020 $26,000.00
Bies, Dr. Robert R. Film Antiretroviral Microbicide Evaluation Federal Flow Through Magee-Womens Research Institute and Foundation 01-Jun-2019 31-May-2020 $131,591.00
Bies, Dr. Robert R. Pharmacokinetics of sedatives - Understanding a modifiable risk factor for pediatric delirium Federal Flow Through Childrens Research Institute 01-Sep-2019 31-Jul-2024 $29,075.00
Blanco, Dr. Javier Contribution of CBRs and AKRs to the Pharmacodynamics of Anthracycline Drugs Federal National Institute of General Medical Sciences 01-Apr-2015 01-Nov-2019 $1,280,301.94
Blanco, Dr. Javier Epigenetic Regulation of FcRn Expression in Human Lung and its Role in the Disposition of Monoclonal Antibody Drugs Federal Eunice Kennedy Shriver National Institute of Child Health & Human Dev 01-Apr-2017 31-Mar-2020 $397,532.00
Blanco, Dr. Javier Defining the Contribution of Cellular Hypoxia to the Cardiotoxicity of Anticancer Anthracyclines and Trastuzumab Federal National Institute of General Medical Sciences 01-Sep-2019 31-Aug-2020 $159,500.00
Blanco, Dr. Javier Understanding the Molecular Underpinnings of Anthracycline-related Cardiomyopathy in Childhood Cancer Survivors Nonfederal Board of Trustees of the University of Alabama Birmingham 01-Feb-2019 31-Jan-2022 $64,369.00
Blanco, Dr. Javier Evaluation of myocardial targets to prevent anthracycline cardiotoxicity in children with Down Syndrome and Leukemia Federal National Cancer Institute 23-Sep-2019 31-Aug-2021 $438,625.00
Blanco, Dr. Javier The Who and Why of Anthracycline-related Cardiotoxicity in Childhood Cancer Survivors Nonfederal Board of Trustees of the University of Alabama Birmingham 01-Jul-2019 30-Jun-2020 $18,561.00
Cha, Dr. Raymond Validation of a Mini-In Vitro Pharmacodynamic Model with Human Serum Constituents and Albumin Nonfederal Alternatives Research & Development Foundation 01-Aug-2019 31-Jul-2020 $39,600.00
Dunn, Dr. Terry E Evaluation of Health Outcomes Associated with a Pharmacist's Telephone Intervention in Transitions of Care in an Underserved Population Nonfederal ASHP Research and Education Foundation 10-May-2016 31-Dec-2019 $20,000.00
Jacobs, Dr. David Matthew Impact of an Integrated Pharmacist and Primary Care Collaborative Transitions of Care Program on Clinical and economic Outcomes among High Risk Patients Nonfederal ASHP Research and Education Foundation 01-Jul-2019 30-Jun-2021 $75,000.00
Jacobs, Dr. David Matthew Impact and feasibility of establishing a Community Health Worker Program within Community Pharmacy Settings Nonfederal Community Pharmacy Foundation 01-Jan-2020 31-Dec-2020 $39,533.00
Jusko, Dr. William J Corticosteroid Pharmacokinetics and Pharmacodynamics Federal National Institute of General Medical Sciences 01-Jul-2015 31-Dec-2019 $2,894,961.00
Jusko, Dr. William J UB-BMS Training Program Nonfederal Bristol Myers Squibb Company 14-Jan-2016 31-Mar-2020 $373,338.00
Jusko, Dr. William J Mechanistic Pharmacokinetics and Pharmacodynamics Federal National Institute of General Medical Sciences 01-May-2019 30-Apr-2024 $2,891,677.00
Krzyzanski, Dr. Wojciech Population PK Model of Indomethaicin in Preterm Infants Nonfederal Childrens Mercy Hospital 14-Nov-2019 13-Nov-2021 $10,000.00
Ma, Dr. Qing Doravirine Cerebrospinal Fluid (CSF) Pharmacokinetics in HIV-Infected Individuals Nonfederal Merck Sharp and Dohme Corporation 04-Jun-2019 04-Jun-2021 $142,500.01
Mager, Dr. Donald E Immunologic and Neurodevelopmental Consequences of Neonatal Anemia and Thrombocytopenia and their Treatments Federal Flow Through Childrens Hospital of Boston 01-Sep-2018 30-Jun-2023 $644,233.00
Mager, Dr. Donald E Tumor Kinetic and Survival/Dropout Modeling of Durvalumab for Multiple Cancer Types Nonfederal MedImmune 16-May-2019 15-May-2021 $39,764.00
Mager, Dr. Donald E Optimizing GVHD Prevention with Systems Pharmacology Models Federal Flow Through Beckman Research Institute of the City of Hope 01-Jun-2019 31-May-2024 $445,407.00
Mager, Dr. Donald E Mechanistic PKPD modelling of biologic treatments in lymphoid leukemia for better understanding of efficacy and safety Foreign Institut de Recherches Internationales Servier 01-Aug-2019 31-Jul-2022 $227,060.00
Mager, Dr. Donald E. Liposomal IL-12 protects melanoma patient-derived tumor-specific T cells from an up regulation of PD-1, exhaustion and loss of function following their adoptive transfer and entry into the tumor microenvironment of melanoma tumor xenografts Non-federal Center for Protein Therapeutics 1-Sep-19 31-Aug-2020 $75,000.00
Meaney, Mr. Calvin J T Regulatory Cell Response to Erythropoiesis Stimulating Agents Post-Renal Transplantation Nonfederal American College of Clinical Pharmacy 01-Nov-2018 31-Oct-2020 $5,000.00
Morris, Dr. Marilyn E Fellowship for Rodriguez Cruz: Gamma-Hydroxybutyrate Toxicokinetics and Toxicodynamics: Drug-Drug Interactions Nonfederal American Foundation Pharmaceutical Education 01-Sep-2019 31-Aug-2020 $10,000.00
Morris, Dr. Marilyn E SBIR: Development of Novel PDE4B Inhibitors to Treat Alcohol Use Disorder Federal Flow Through Codex BioSolutions Incorporated 23-Sep-2019 22-Sep-2021 $73,459.00
Morris, Dr. Marilyn E. Hepatic FcRn and the Impact of its Loss on FcRn-Mediated Recycling Non-federal Center for Protein Therapeutics 1-Sep-19 31-Aug-2020 $38,500.00
Morris, Dr. Marilyn E. BCSFB transport and disposition of IgG1 Non-federal Center for Protein Therapeutics 1-Sep-19 31-Aug-2020 $75,000.00
Morse, Dr. Eugene University of Rochester HIV/AIDS Clinical Trials Unit Federal Flow Through University of Rochester 01-Dec-2013 29-Feb-2020 $444,684.00
Morse, Dr. Eugene Clinical Pharmacology Quality Assurance Federal National Institute of Allergy & Infectious Disease 30-May-2015 29-May-2020 $10,904,068.00
Morse, Dr. Eugene HIV Research Training Program Federal Fogarty International Center 01-Apr-2016 28-Feb-2021 $1,884,534.00
Morse, Dr. Eugene Global Infectious Diseases Research Training Program Federal Fogarty International Center 11-Apr-2018 28-Feb-2023 $1,125,653.00
Morse, Dr. Eugene Center for Health + Technology (CHeT) Nonfederal University of Rochester 01-Jul-2018 30-Jun-2020 $12,000.00
Morse, Dr. Eugene Laboratory Center (LC) , AIDS Clinical Trails Group (ACTG) [UM1AI106701] Federal Flow Through University of California at Los Angeles 01-Dec-2018 30-Nov-2020 $683,700.00
Morse, Dr. Eugene ACTG Precautionary and Prohibited Medications Database Federal Flow Through University of California at Los Angeles 01-Dec-2018 29-Feb-2020 $233,684.00
Qu, Dr. Jun Modeling Mechanisms of Adjuvanted Influenza Vaccine Induced IgG Repertoire Diversity and Heterosubtypic Immunity URF (AWD00001405) Federal Flow Through University of Rochester 01-Feb-2017 31-Jan-2022 $467,931.00
Qu, Dr. Jun GMPS-GMPR axis melanoma progression and therapy Federal Flow Through Wake Forest University Health Sciences 23-Nov-2018 30-Apr-2023 $103,026.00
Qu, Dr. Jun Comprehensive characterization of upregulated proteases in diseased vs normal tissues Nonfederal AbbVie Incorporated 19-Jun-2019 18-Jun-2020 $190,000.00
Qu, Dr. Jun Novel LC-MS strategies for comprehensive investigations of Circulating Immune Complext and MHC Presenting Peptides Nonfederal GlaxoSmithKline 08-Jul-2019 01-Jun-2021 $289,493.00
Qu, Dr. Jun 3D-printed micro scaffold for high-resolution tissue compartmentalization / micro-sampling and application in measuring the tissue distribution of protein biotherapeutics and biomarkers Non-federal Center for Protein Therapeutics 1-Sep-19 31-Aug-20 $100,000.00
Qu, Dr. Jun Pharmacokinetics of indomethacin for PDA closure in extremely preterm infants Foreign University of Manitoba 06-Jun-2019 31-May-2020 $20,405.60
Qu, Dr. Jun UB CAT: Epigenetic Drug Discovery Platform For Methylation Inhibitors Non-federal CH3 BioSystems LLC 01-Jan-2020 30-Jun-2020 $7,500.00
Qu, Dr. Jun Neuroinflammation-related phosphoprotein signaling pathways as potential therapeutic targets for GWI using an established animal model Federal Flow Through West Virginia Univ. Research Corp. on behalf of West Virginia Univ. 01-Feb-2020 31-Jan-2021 $103,669.00
Ramanathan, Dr. Murali Adherence Modeling of Digital Medicine Data Nonfederal Otsuka Pharmaceutical Development and Commercialization Inc 18-Sep-2017 01-Sep-2022 $107,713.00
Shah, Dr. Dhaval K. Evaluation of Brain Pharmacokinetics of Protein Therapeutics after Local Administration Non-federal Center for Protein Therapeutics 1-Sep-19 31-Aug-20 $100,000.00
Shah, Dr. Dhaval K. Effect of Charge Variation on the Disposition of Monoclonal Antibodies Non-federal Center for Protein Therapeutics 1-Sep-19 31-Aug-20 $38,500.00
Shah, Dr. Dhaval K. Evaluation of pH Dependent Antigen Binding and Geldanamycin Co-administration as Novel Strategies for Enhanced Intracellular Delivery of Antibody-Drug Conjugates (ADCs) Non-federal Center for Protein Therapeutics 1-Sep-19 31-Aug-20 $100,000.00
Shah, Dr. Dhavalkumar Translational Systems Pharmacokinetic Models of Novel Anticancer Biologics Federal National Institute of General Medical Sciences 01-May-2015 31-Mar-2020 $1,650,448.00
Shah, Dr. Dhavalkumar Fellowship: Ashwni Verma Nonfederal Oncolinx LLC 10-Jul-2018 09-Jul-2019 $87,150.00
Sprowl, Dr. Jason Arthur Regulation of SGLT1 function by tyrosine kinase inhibitors Nonfederal American Association of Colleges of Pharmacy 01-Feb-2019 31-Jan-2020 $9,864.00
Straubinger, Dr. Robert M Tumor priming sequences combined with novel nanoparticle drug carriers for enhanced therapeutic efficacy in pancreatic cancer Federal National Cancer Institute 01-Jul-2015 31-Aug-2020 $2,156,820.00
Straubinger, Dr. Robert M Ipsen Es1e 2017-19 Nonfederal Ipsen Bioscience Incorporated 01-Mar-2017 31-Aug-2020 $12,645.00
Straubinger, Dr. Robert M Large-scale proteome-wide analysis with high accuracy/precision to guide pancreatic cancer therapy development Federal National Cancer Institute 21-Dec-2018 30-Nov-2020 $398,683.00
Tornatore-Morse, Dr. Kathleen M Age and Race Influences on Immunosuppression after Renal Transplant Federal National Institute on Aging 15-Aug-2018 30-Jun-2023 $3,507,814.00
Tsuji, Dr. Brian T Novel PK/PD Strategies for Polymyxin Combinations against Gram-negative Superbugs Federal National Institute of Allergy & Infectious Disease 01-Apr-2014 31-Mar-2020 $4,448,044.00
Tsuji, Dr. Brian T Novel Strategies for Antibiotic Combinations to Combat Gram-negative Superbugs Federal National Institute of Allergy & Infectious Disease 20-Dec-2019 30-Nov-2024 $3,920,362.00
Xu, Dr. Ying SBIR - Phosphodiesterase-4B (PDE4B) Inhibitors for Psychiatric Disease Federal Flow Through Tetra Discovery Partners 20-Sep-2016 31-Aug-2020 $642,120.48
You, Dr. Young Jae NIR-activatable Prodrugs for Treating Peritoneally Metastasized Ovarian Cancers Federal National Institute of General Medical Science 01-Mar-2015 31-Jan-2021 $147,604.00

Updated April 1, 2020
Data provided by University at Buffalo Sponsored Projects Services