This virtual symposium brings together scientists interested in quantitative systems pharmacology (QSP) to present and discuss contemporary approaches, including the challenges and opportunities for advancing the science and practice of QSP. It is hoped the symposium serves to stimulate collaborations and synergies amongst its participants to promote discoveries in the field of QSP.
The 2021 symposium is our fourth annual and, though virtual, remains a free event.
We look forward to your participation!
Jim Gallo, 2021 QSP Symposium Organizer
Donald Mager, 2021 QSP Symposium Co-Organizer
8:45 a.m. | Welcome |
9:00 a.m. | Doug Lauffenburger Systems Biology Modeling Approaches for Preclinical-to-Clinical Translation |
9:45 a.m. | Oleg Milberg QSP modeling and the search for accuracy and precision: when a lot is not enough |
10:30 a.m. | Break |
10:45 a.m. | Edward Stites A systems mechanism for KRAS mutant allele-specific responses to targeted therapy |
11:30 a.m. | Stacey Finley Predicting the impact of heterogeneity on the tumor-immune microenvironment |
12:15 p.m. | Break |
12:20 p.m. | Trainee Speaker 1 Identification of Spike-ACE2 binding allosteric modulators using in silio method Jingchen Zhai, University of Pittsburgh |
12:35 p.m. | Trainee Speaker 2 In Silico Pharmacological Assessment of Mibefradil in Single Detrusor Smooth Muscle Cell towards Understanding Urinary Bladder Over Activity Chitaranjan Mahapatra, Cardiovascular Research Institute, University of California San Francisco |
12:50 p.m. | Trainee Speaker 3 Prediction of monocarboxylate transporter-mediated pharmacokinetics of gamma-hydroxybutyric acid (GHB) in patients with impaired renal function using a PBPK model Tianjing Ren, University at Buffalo |
8:45 a.m. | Trainee Speaker 4 A New Approach for In Silico Prediction of Oral Drug Concentration Profiles in Human for Drug Candidates Lack Experimental Pharmacokinetic Data Beihong Ji, University of Pittsburgh |
9:00 a.m. | Kevin Wood Emergence and control in microbial communities: steering bacterial pathogens through the phenotype space of multidrug resistance |
9:45 a.m. | Thomas Yankeelov Tumor Forecasting via Quantitative Imaging and Mathematical Modeling |
10:30 a.m. | Break |
10:45 a.m. | Aaron Meyer Deeply profiling pharmacodynamic response with single cell dynamics |
11:30 a.m. | Ashlee Ford-Versypt Computational Modeling of the Gut-Bone Axis and Implications of Butyrate Treatment on Osteoimmunology |
12:15 p.m. | Break |
12:20 p.m. | Kathryn Miller-Jensen Integrating Single-Cell Measurements for Immunology |
Four trainee speakers will present their QSP research and will be selected from Abstract solicitations. Trainees must be a student or postdoctoral fellow and a major contributor to the work. Please send a title, authors, affiliations, and a 150 word abstract to Jim Gallo (jmgallo@buffalo.edu) by July 1, 2021 for consideration.
Jim Gallo, Empire Innovation Professor, Pharmaceutical Sciences: (jmgallo@buffalo.edu)