16th Buffalo Pharmaceutics Symposium

6:00 p.m.
Welcome Reception and Dinner
The Atrium @ Rich's*
1 Robert Rich Way
Buffalo, NY  14213
View map and directions

*Shuttle transportation will be available to Rich's from the Hyatt Place Buffalo/Amherst departing at 5:30 p.m. Shuttle will depart from Rich's to return to the Hyatt Place Buffalo/Amherst at approximately 9:15 p.m.

190 Pharmacy Building, UB South Campus*

*Shuttle transportation will be available for Hyatt Place guests to and from the Pharmacy Building, departing from the hotel at 8:00 a.m. and then departing from the Pharmacy Building at 5:15 p.m.

8:30 a.m.
Registration/Continental Breakfast

9:00 a.m.
Introduction

Session 1: Vision and Legacy of Dr. Jusko: PK/PD and Systems Pharmacology
Co-Chairs: Sukyung Woo, PhD, Professor, Department of Pharmaceutical Sciences, University at Buffalo; Yanguang "Carter" Cao, PhD, Associate Professor, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC

9:05 a.m.
Talk 1: Dr. William Jusko
William J. Jusko, PhD, SUNY Distinguished Professor, Department of Pharmaceutical Sciences, University at Buffalo

9:35 a.m.
Talk 2: Critical Breakthroughs in Corticosteroid Pharmacology that Impacted Asthma Therapy
Stanley J. Szefler, MD, Professor Professor of Pediatrics, University of Colorado Anschutz School of Medicine, Aurora, Colorado

9:55 a.m.
Talk 3: The Impact of Quantitative Systems Pharmacology Modeling on the Design and Optimization of Gene Therapy Approaches
Guy Meno-Tetang, PhD, Senior Scientific Director of Clinical Pharmacology at Neurocrine Biosciences, San Diego, CA 

10:15 a.m.
Coffee Break

10:45 a.m.
Talk 4: Antibiotic PK/PD: From Traditional Indices Towards Systems Pharmacology
Cornelia Landersdorfer, PhD, Associate Professor, Drug Delivery Disposition & Dynamics, Centre to Impact Antimicrobial Resistance, Monash University, Victoria, Australia

11:05 a.m.
Talk 5: Model Informed mRNA Therapeutics Development
Wei Gao, PhD, Executive Director, Head of Clinical and Quantitative Pharmacology, Moderna

11:25 a.m.
Talk 6: Machine Learning for Predicting Clinical Adverse Events Using On-/Off-Target Engagement and Tissue Selectivity
Natalie Jusko, MA, Doctoral Candidate, Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, MI

12:00 p.m.
Lunch/Group Photo
Alumni Mentoring Session

Session 2: Division of Drug Delivery and Pharmaceutical Bioengineering
Co-Chairs: Sathy Balu-Iyer, PhD, Professor and Division Head, Division of Drug Delivery and Pharmaceutical Bioengineering, Department of Pharmaceutical Sciences and Associate Dean of Research, University at Buffalo School of Pharmacy and Pharmaceutical Sciences; Yeh-Hsing "Sima" Lao, PhD, Assistant Professor, Department of Pharmaceutical Sciences, University at Buffalo

2:00 p.m.
Talk 1: Dr. Zhenjia Wang
Zhenjia Wang, PhD, Professor of Empire Innovation, Department of Pharmaceutical Sciences, University at Buffalo

2:45 p.m.
Talk 2: Engineering the Pharmacokinetics and Intravascular Distribution of Anti-Thrombotic Agents 
Patrick Glassman, PhD, Assistant Professor, Pharmaceutical Sciences, Temple University, Philadelphia, PA 

3:15 p.m.
Coffee Break

3:45 p.m.
Talk 3: Growing Evidence: Development of Dupilumab for Adolescents with Type 2 Inflammatory Diseases
Matthew Kosloski, PhD, Senior Director of Clinical Pharmacology, Regeneron

4:15 p.m.
Talk 4: Dr. Vivek Purohit
Vivek Purohit, PhD, Associate Vice President, Clinical Pharmacology & Biopharmaceutics, Incyte

6:30 - 9:00 p.m.
Symposium Cocktail Dinner
Buffalo Museum of Science*
1020 Humboldt Parkway
Buffalo, NY  14211
View map and directions

*Shuttle transportation will be available to the Buffalo Museum of Science from the Hyatt Place Buffalo/Amherst departing at 6:00 p.m. Shuttle will depart from the Buffalo Museum of Science to return to the Hyatt Place Buffalo/Amherst at approximately 9:15 p.m.

190 Pharmacy Building, UB South Campus*

*Shuttle transportation will be available for Hyatt Place guests to and from the Pharmacy Building, departing from the hotel at 8:00 a.m. and then departing from the Pharmacy Building at 5:15 p.m.

8:30 a.m.
Registration/Continental Breakfast

Session 3: Division of Drug and Biotherapeutic Discovery
Co-Chairs: Anne Talkington, PhD, Assistant Professor, Department of Pharmaceutical Sciences, University at Buffalo; Youngjae You, PhD, Professor of Empire Innovation, Department of Pharmaceutical Sciences, University at Buffalo

9:00 a.m.
Talk 1: Dr. Bhaskar Das 
Bhaskar Das, PhD, Professor and Division Head, Division of Drug and Biotherapeutic Discovery, Department of Pharmaceutical Sciences, University at Buffalo

9:45 a.m.
Talk 2: PMxAgent: An Agentic Platform for Pharmacometrics
Peter Bloomingdale, PhD, Senior Principal Scientist, Generate Biomedicines

10:15 a.m.
Coffee Break

10:45 a.m.
Talk 3: Translational Strategies Enabling Early Clinical Development
Lisa Benincosa, Senior Vice President Clinical Strategy, Allucent, and Antje Walz, Founder and Chief Exeuctive Officer, tkc suisse GmbH

11:15 a.m.
Talk 4: Immune Dysregulation as a Multiscale Optimization Problem
Anne Talkington, PhD, Assistant Professor, Department of Pharmaceutical Sciences, University at Buffalo

12:00 p.m.
Lunch

Session 4: Division of Molecular Biosciences
Co-Chairs: Xinning Yang, PhD, Policy Lead in Guidance and Policy Team, Office of Clinical Pharmacology, U.S. Food and Drug Administration; Carrie Hoefer, PhD, MBA, Clinical Assistant Professor, Department of Pharmaceutical Sciences and Associate Dean of Undergraduate and Online Pharmacy Programs, University at Buffalo School of Pharmacy and Pharmaceutical Sciences

2:00 p.m.
Talk 1: Cannabidiol: Potential for Drug-Drug Interactions and Use in Smoking Cessation
Philip Lazarus, PhD, Professor and Division Head, Division of Molecular Biosciences, Department of Pharmaceutical Sciences, University at Buffalo

2:45 p.m.
Talk 2: Modulation of GHB Toxicokinetics by Sex and Hormone Exposure: Mechanistic Insights into Overdose Risk
Melanie Felmlee, PhD, Director of Pharmacogenomics, Professor of Pharmaceutical Sciences and Pharmacogenomics, Department of Pharmaceutical and Graduate Life Sciences, Manchester University

3:15 p.m.
Coffee Break

3:45 p.m.
Talk 3: Applications of Cellular Assays for Understanding Drug Disposition of Protein Therapeutics
Mark Bryniarski, PhD, Senior Principal Scientist, Amgen

4:15 p.m.
Talk 4: Application of Semi-Mechanistic PK/PD Models for Ophthalmology in Drug Discovery & Early Development
Robert Jones, PhD, Principal Scientist, Drug Metabolism & Pharmacokinetics, Genentech, San Francisco, CA

4:45 p.m.
Closing Remarks

5:30 p.m.
Special Event Honoring Dr. William Jusko*
Jazzboline Restaurant & Bar
5010 Main St.
Amherst, NY  14226
View map and directions

Join us as we celebrate the establishment of a new endowment honoring Dr. William Jusko, a world-renowned pioneer, mentor and educator whose five-decade legacy has shaped generations of scientists.

*All speakers, attendees, faculty, staff, guests, and children are invited to this complimentary event.