May 11 - 13, 2026
Our classic 3-day course on the concepts and applications of PK/PD modeling will be presented on a level suitable for those knowledgeable in basic pharmacokinetics.
Registration opens late January 2026
We present the theory and applications of pharmacodynamics. With diverse pharmacokinetic-pharmacodynamic (PK/PD) modeling concepts it is possible to describe and predict the time course of drug effects under various physiological and pathological conditions. The study of PK/PD and Disease Progression relationships can be of considerable value in understanding drug action, summarizing extensive data, building a knowledge repository, finding optimal dosing regimens, and in making predictions under new circumstances. More advanced PK/PD models have evolved into Systems Pharmacology.
William J. Jusko, PhD
Dr. Jusko is SUNY Distinguished Professor of Pharmaceutical Sciences at the University of Buffalo and Director of the Center of Excellence in Pharmacokinetics and Pharmacodynamics. He is the former Editor-in-Chief of JPKPD, has authored over 650 publications, and consults for the FDA, NIH, and the pharmaceutical industry. His research emphasizes PBPK modeling, protein therapeutics and immunosuppressive drugs.
Donald E. Mager, PharmD, PhD
Dr. Mager is Chair and Professor of Pharmaceutical Sciences at the University at Buffalo. He is CEO of ePD and past president of ISoP and ACCP and has served as Visiting Professor at the Université Paris Descartes and on the Advisory Committee on Clinical Pharmacology to the FDA. His research invokes PK/PD systems analysis with particular interest in anti-cancer therapy and immunomodulatory pharmacotherapy.
All times listed are Eastern Standard Time (EST)
| Time | Event |
|---|---|
| 08:00-08:30 | Continental Breakfast/Registration |
| 08:30-08:45 | Dr. W.J. Jusko: Introductions |
| 08:45-09:45 | Dr. W.J. Jusko: Overview of PK/PD |
| 09:45-10:45 | Dr. D. Mager: Art of Modeling |
| 10:45-11:00 | Coffee |
| 11:00-12:00 | Dr. D. Mager: Basic Pharmacology |
| 12:00-01:00 | Lunch |
| 01:00-02:00 | Dr. W.J. Jusko: Modeling Biophase Distribution |
| 02:00-03:00 | Dr. W.J. Jusko: Basic Indirect Response Models |
| 03:00-03:15 | Break |
| 03:15-04:15 | Dr. D. Mager: Modeling Transduction Processes |
| 04:15-05:15 | Dr. W.J. Jusko: Slow & Irreversible Effects |
| 05:15-06:00 | Cocktail Reception |
| 06:00-07:30 | Group Dinner |
All times listed are Eastern Standard Time (EST)
| Time | Event |
|---|---|
| 08:00-08:30 | Continental Breakfast |
| 08:30-09:45 | Dr. D. Mager: Review & Exercises I |
| 09:45-10:00 | Coffee |
| 10:00-11:00 | Dr. W.J. Jusko: Chemotherapy Models |
| 11:00-12:00 | Dr. W.J. Jusko: Indirect Response Complexities |
| 12:00-01:00 | Lunch |
| 01:00-02:00 | Dr. W.J. Jusko: Modeling Tolerance Processes |
| 02:00-03:00 | Dr. D. Mager: Target-Mediated PK/PD Models |
| 03:00-03:15 | Refreshments |
| 03:15-04:15 | Dr. W.J. Jusko: Modeling Drug Interactions |
| 04:15-05:15 | Pf. J. Fiedler-Kelly: Population PK/PD Models |
All times listed are Eastern Standard Time (EST)
| Time | Event |
|---|---|
| 08:00-08:30 | Continental Breakfast |
| 08:30-09:45 | Dr. W.J. Jusko: Review & Exercises II |
| 09:45-10:00 | Coffee |
| 10:00-11:00 | Dr. D. Shah: PKPD Monoclonal Antibodies |
| 11:00-12:00 | Dr. W.J. Jusko: Disease Progression Models |
| 12:00-01:00 | Lunch |
| 01:00-02:00 | Dr. D. Mager: Species Scaling in PKPD |
| 02:00-03:00 | Dr. J. Earp: FDA & Pharmacometrics |
| 03:00-03:15 | Refreshments |
| 03:15-04:15 | Dr. D. Mager: Systems Modeling in PK/PD |
| 04:15-04:30 | Dr. W.J. Jusko: Final Discussion and Summary |
The course will be held in person at:
The Niagara Falls Convention Center (NFCC)
101 Old Falls Street
Niagara Falls, NY 14303
USA
Phone: (716) 278-2100
Fax: (716) 278-0008
The Center is 28 minutes from Buffalo Niagara International Airport.
Several nearby hotels within walking distance are available. Please book directly as soon as registered for this course. Possible hotels include:
Laptops recommended.
Individual fee: $2,800. This includes course documentation, continental breakfasts, mid-session refreshments, lunches and opening dinner. Up to 5 graduate students may enroll at $1,400 (registered MS and PhD).
Online registration will begin January 26, 2026. The course is limited to the capacity of 40 participants. Confirmation email of registration will be returned upon successful registration and payment.
Mastercard, Visa, American Express, and Discover card payments will be accepted.
Cancellations with a full refund may be made until March 16, 2026. No refund is possible on cancellations received after this date. Substitutions may be made at any time.
Contact UB course secretary Suzette Mis at (716) 645-4834 or mis@buffalo.edu if you need assistance.


