Researchers in New York have investigated the mechanism of action of extracellular vesicles, also called exosomes, secreted by mesenchymal stem cells (MSC). Their research highlights that MSC-derived exosomes involved in cardiac regeneration act by an increase in angiogenesis, an anti-apoptotic effect on cardiomyocytes, cell proliferation, and a decrease of collagen production by cardiac fibroblasts.
