The Division of Drug and Biotherapeutic Discovery focuses on the identification, synthesis, and development of innovative small and macromolecular compounds to be used as probes, adjuvants, and/or potential drugs for the ultimate diagnosis or treatment of complex unmet medical needs.

The Division of Drug Delivery and Pharmaceutical Bioengineering focuses on the development of innovative biocompatible delivery systems for improving the safety and efficacy of existing or new therapeutic modalities from small molecule to biological drugs including proteins, genes, and cell-based therapies.

The Division of Pharmacokinetics-Pharmacodynamics and Systems Pharmacology focuses on the time-course and relationships between drug disposition and pharmacological effects using theoretical and applied pharmacometric modeling to guide drug development, translate nonclinical data to humans, explain sources of inter-patient variability, and optimize dosing regimens in subpopulations and individual patients.

The Division of Molecular Biosciences focuses on examining mechanisms influencing an individual’s risk for disease, the beneficial response to therapeutic regimens, and the manifestation of adverse drug reactions, through lab-based as well as clinical studies and the generation and integration of large-scale experimental data, such as genomic, proteomic, and metabolomic signatures.