Stewardship of Proton Pump Inhibitors: Considerations for Use and Deprescribing

Long-term use of proton pump inhibitors (PPIs) without an ongoing indication or evidence of benefit contributes to increased pill burden, increased medication-related costs, and potential adverse effects. This written article reviews FDA-approved labeling for PPIs, summarizes treatment guidelines regarding appropriate dosage and duration of treatment, and is designed to help learners identify appropriate indications for long-term use of PPIs. In the absence of an indication for long-term use, recommendations are provided to assist with developing patient-specific plans to deprescribe PPIs and manage symptoms.

1. Identify the appropriate dosing and duration of PPIs based on FDA-approved indications and guideline recommendations.
2. Discuss considerations for long-term PPI therapy.
3. Determine when deprescribing of PPIs is appropriate based on patient-specific factors.

Program components are:

• Pre-test
  
• Article
  
• Post-test
• Evaluation

Achieving a passing score on the pre-test is not a requirement. Credit will be awarded upon successful completion of the post-test activity, with a score of 70% or better.

Brenda Basile, PharmD, MS
Research Scientist
University at Buffalo School of Pharmacy and Pharmaceutical Sciences

Holly Coe, PharmD
Clinical Assistant Professor
University at Buffalo School of Pharmacy and Pharmaceutical Sciences

Alexia Sroka, PharmD, BCPS
Coordinator, MPEP
University at Buffalo School of Pharmacy and Pharmaceutical Sciences

There is no fee associated with this program.

ACCREDITATION FOR PRESCRIBERS:

The University at Buffalo Jacobs School of Medicine and Biomedical Sciences is accredited by the ACCME to provide continuing medical education for physicians.

CERTIFICATION

The University at Buffalo Jacobs School of Medicine and Biomedical Sciences designates this Internet Enduring Material activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)TM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.

ACCREDITATION FOR PHARMACISTS:

The University at Buffalo School of Pharmacy and Pharmaceutical Sciences is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. This knowledge-based activity has been assigned ACPE # 0044-0000-23-033-H01-P and will award 1.0 contact hour (0.10 CEU) of home study continuing pharmacy education credit. Credit will be uploaded to the CPE Monitor for those who complete all components of this activity.

Release date:  8/14/2023

Expiration date:  8/13/2026

Please email questions to pharmacyce@buffalo.edu