Research conducted at the Neurologic Institute focused to neuropharmacology and a clinical research interest in PK-PD of neuroactive compounds.
1. Ethanol Pharmacology: Conducts clinical studies to examine the pharmacokinetic and pharmacodynamic models of ethanol pharmacologic effects.
2. Headache: Clinical management models for headache pharmacotherapy.
3. Alzheimer‘s: Clinical management models for Alzheimer‘s pharmacotherapy.
Education and Training:
Postdoctoral fellowship, University at Buffalo, department of pharmaceutical sciences/Millard Fillmore Hospital (1981)
PharmD, Philadelphia College of Pharmacy & Science, Cum laude (1979)
PharmD, The State University of NY at Buffalo, Cum laude (1977)
Awards and Honors:
J. J. Teter Fish Conservation Award (1993)
George Thorn MD Award (1993)
Rho Chi Excellence in Teaching Award (1992)
Faculty Dedication, UB School of Pharmacy Yearbook (1991)
Fellow, American College of Clinical Pharmacology (1989)
McKeen Cattell Memorial Distinguished Achievement Award (1989)
Gengo FM; Robson M; Gengo MF; Forrest A; Rainka MM; Hourihane JM; Bates V. Prevalence of platelet nonresponsiveness to aspirin in patients treated for secondary stroke prophylaxis and in patients with recurrent ischemic events. J Clin Pharmacol. 2008; 48.
Gengo FM; Rubin L; Robson M; Rainka M; Mager DE; Bates V. Effects of Ibuprofen on the Magnitude and Duration of Aspirin`s Inhibition of Platelet Aggregation: Clinical Consequences in Stroke Prophylaxis. J Clin Pharmacol. 2008; 48.
Hong Y; Gengo FM; Rainka MN; Bates VE; Mager DE. Population pharmacodynamic modelling of aspirin- and Ibuprofen-induced inhibition of platelet aggregation in healthy subjects. Clin Pharmacokinet. 2008; 47.
Gengo FM. Effects of Ibuprofen on Sleep Quality as Measured Using Polysomnography and Subjective Measures in Healthy Volunteers. Clinical Therapeutics 2007 Vol 28 No 11 1820-1826. 2007; 28.
Blair ML, Hisa H, Sladek CD, Radke KJ, Gengo FM. Dual adrenergic control of renin during nonhypotensive hemorrhage in conscious dogs.. Am J Physiol. 1991; 260(6 Pt).
Gengo FM, Fagan SC, Hopkins LN, Wagner D, Schuster DP. Nonlinear distribution of atenolol between plasma and cerebrospinal fluid.. Pharm Res. 1989; 6(3).
Morris ME, Gengo FM, Kinkel WR, Castellani DA, Levy G. Effect of acetaminophen on inorganic sulfate concentrations in human cerebrospinal fluid.. J Pharm Sci. 1986; 75(7).
Gengo FM, Ziemniak MA, Kinkel WR, McHugh WB. High-performance liquid chromatographic determination of metoprolol and alpha-hydroxymetoprolol concentrations in human serum, urine, and cerebrospinal fluid.. J Pharm Sci. 1984; 73(7).
Books and Book Chapters:
Gengo FM. Pharmacologic principles and treating neurologic disease. Neurology in clinical practice. 2008; 1.
Gengo FM; Iyer VS; Mathew R; Michael G; Michelle RM; Forrest A. Effects of Naproxin on the Time Course of Aspirin Induced Inhibition of Platelet Aggregation. 110th Annual Meeting American Society of Clinical Pharmacology and Therapeutics. 2009.
Gengo FM; Michelle RM; Mathew R; Michael GF; Joseph HM; Vernice B. Response to Increased Aspirin Dose in Patients whose Platelets were Non Responsive to Low Dose Aspirin. Stroke, Apr 2009; 40: e105 - e276. 2009; 40.
Burstein AH, Hatton M, Modica R, Gengo FM. Plasma Concentration Profile, and Effects on Dental Procedure Associated Anxiety, of Intranasally Administered Midazolam. Proceedings of the American Dental Society of Anesthesiology 1996. 1994.
Evaluative Studies and Case Reports:
Gengo FM, Fagan SC, Kinkel WR, McHugh WB. Serum concentrations of propranolol and migraine prophylaxis.. Arch Neurol. 1984; 41(12).
American College of Clinical Pharmacology; Fellow (1988)
American College of Clinical Pharmacology; Fellow (1988–present)
American Association of Pharmaceutical Scientists (1986–present)
American College of Clinical Pharmacy (1982)
American College of Clinical Pharmacy (1982–present)
American Society of Clinical Pharmacology and Therapeutics (1981)
American Society of Clinical Pharmacology and Therapeutics (1981–present)
American Federation for Clinical Research (1981–present)
"PHARMACOKINETIC POST MORTUM EVALUATION REVEALS DEATH OF A TODDLER FROM CARBAMAZEPINE TO BE ACCIDENTAL RATHER THAN CRIMINAL" American Academy of Forensic Sciences (2012)
"AN ASSAY TO ASSESS ANTIPLATELET EFFECTS OF DIPYRIDAMOLE AT THERAPEUTIC CONCENTRATIONS" American College of Clinical Pharmacology (2010)
"CLOPIDOGREL ENHANCES PLATELET RESPONSIVENESS TO ASPIRIN." American College of Clinical Pharmacology (2010)
"EFFECTS OF NAPROXIN ON THE TIME COURSE OF ASPIRIN INDUCED" American Society of Clinical Pharmacology and Therapeutics (2010)
"PLATELET RESPONSE TO INCREASED ASPIRIN DOSE IN PATIENTS WHOSE PLATELETS WERE NON-RESPONSIVE TO LOWER ASPIRIN DOSES" American Society of Clinical Pharmacology and Therapeutics (2010)
"THE PREVALENCE OF PLATELET NON-RESPONSIVENESS TO CLOPIDOGREL AND THE EFFECT OF CYTOCHROME P450 1A2 INDUCING MEDICATIONS" American College of Clinical Pharmacology (2010)
Department of Pharmacy Practice Promotion Committee; Other (2010)
Faculty Search Committee; Identify and recruit new Departmental Faculty with trainning and research interests in Cardiology Successfully recruited to new fatty members; Other (2007)