Pharmaceutical Sciences Research Centers and Facilities

The Center for Drug Delivery is a dynamic academic home for investigators interested in discovering and advancing innovative drug delivery and therapy strategies.

The Center of Excellence in Pharmacokinetics and Pharmacodynamics promotes the development and application of PK/PD to the problems and challenges of drug therapy.

The Center for Protein Therapeutics (CPT) works with leading pharmaceutical companies to advance the development of next-generation protein drugs, providing improved effectiveness and convenience for users.

Computation and visualization play a key role in the educational and research activities of The Department of Pharmaceutical Sciences and the UB School of Pharmacy and Pharmaceutical Sciences. The department, school, and university have invested extensively in computational and visualization resources.

Through a grant from the National Institutes of Health, Division of Research Resources, our faciltiy has a state-of-the-art CD instrument, operated as a shared facility. This instrument is a JASCO J-715, with the capability for simultaneous CD/fluorescence data acquisition, 4-channel stopped flow, titrator, fast-responding peltier-effect temperature control, and full computer control of experimental setup and data acquisition.

The facility serves a variety of research projects. A major focus and area of local expertise is the analysis of biological and artificial lipid bilayer membranes (liposomes). DSC is particularly useful in the investigation of small-molecule/membrane interactions. TGA can be used to detect residual solvent in amorphous and crystalline solids, and to characterize some polymorphic states such as solvates.

The facility serves a variety of research projects involving protein structure, drug-protein interactions, biological membrane structure and function, and pharmaceutical formulation.

We have re-organized our facilities, concentrating our triple-quadrupole/small molecule analysis resources on the UB South Campus (314B Kapoor Hall) and creating a core facility focused upon proteomics and ultra-high sensitivity biopharmaceutical analysis on the UB Downtown Campus, located in the NY State Center of Excellence in Bioinformatics and Life Sciences.