Research

Research

At the UB School of Pharmacy and Pharmaceutical Sciences, our dynamic research spans drug interaction, from discovery to development to clinical application. We are leading developments in precision pharmacotherapy, resulting in improved patient outcomes and improvements for future public policy initiatives.

We are proud of our world-renowned researchers who challenge scientific boundaries and define the future of medication research. Our top 25 research institution ranking by the American Association of Colleges of Pharmacy for total extramural funding and National Institutes of Health grant support gives us a powerful foundation that facilitates groundbreaking discoveries and solutions to critical health challenges.

We have robust research centers in pharmacy practice and pharmaceutical sciences.  Major federal and external programmatic funding sustain the valuable work conducted in these areas.

Our school houses individual faculty research laboratories, as well as shared resources within the school, university and major local research institutions.

KEY RESEARCH STRENGTHS

PK/PD, Pharmacometrics and Systems Pharmacology

Collectively, our research in pharmacokinetics and pharmacodynamics (PK/PD), pharmacometrics, and systems pharmacology is having a critical impact on important decision making in drug discovery, development, and clinical utilization and is being used to guide the design of new potential drugs, provide a scientific rationale for new drug combinations, minimize adverse drug reactions, and individualize pharmacotherapy.

Pharmacogenetics, Genomics, Drug Metabolism and Drug Transport

We employ a unique multi-disciplinary approach to these areas of research which study individuals response to particular drugs based on their genomic profile, allowing for the evaluation of genetic variables affecting a person’s response to that particular drug. These approaches combine pharmacology and genomics, providing the key foundational principles of precision medicine.

Protein Therapeutics

We are conducting cutting-edge research that tests hypotheses relating to the pharmacokinetics and pharmacodynamics (PK/PD) of protein drugs, and also relating to the development of new methods for the prediction and characterization of protein PK/PD.

Drug Delivery

Our research is transformative in the development of drug delivery systems for the targeted delivery of therapeutic agents. With a focus on the on the development of protein therapeutic delivery systems as a bio-therapeutic pathways, this research will expand options in the delivery of multiple therapeutic agents and approaches to gene therapy.

Pharmaceutical Health Services and Outcomes Research

We focus on the intersection of pharmaceutical health services and outcomes research, pharmacoepidemiology, comparative effectiveness research and implementation science. Our faculty investigate the impact and outcomes of pharmaceutical products and services while advancing the knowledge about the effectiveness and safety of medicines as well as pharmacy’s role in improving population health. Our approach emphasizes interdisciplinary and collaborative research strategies encompassing both observational and interventional methods across a variety of therapeutic areas.

Clinical and Translational Research

We are accelerating the delivery of basic scientific discoveries from the laboratory to clinical trials, and from clinical trials into general practice.  Our faculty are conducting extensive research in preclinical and early clinical development for novel compounds for investigators.