Monday, May 13 - Wednesday, May 15, 2019
Niagara Falls, NY
Our classic 3-day course on the concepts and applications of PK/PD modeling will be presented on a level suitable for those knowledgable in basic pharmacokinetics.
We present the theory and applications of pharmacodynamics. With diverse pharmacokinetic-pharmacodynamic modeling concepts it is possible to describe and predict the time course of drug effects under various physiological and pathological conditions. The study of PK/PD and Disease Progression relationships can be of considerable value in understanding drug action, summarizing extensive data, building a knowledge repository, finding optimal dosing regimens, and in making predictions under new circumstances. More advanced PK/PD models have evolved into Systems Pharmacology.
Special Note: We are offering this course and hotel venues adjacent to Niagara Falls with a large array of vacation activities including casinos. Bring your family!
William J. Jusko, PhD
Dr. Jusko is SUNY Distinguished Professor of Pharmaceutical Sciences at the University of Buffalo and Director of the Center of Excellence in Pharmacokinetics and Pharmacodynamics. He is Editor-in-Chief of JPKPD, has authored over 600 publications, consults for the FDA, NIH, and the pharmaceutical industry, and is listed in ISI Most Highly Cited in Pharmacology.
Donald E. Mager, PhD
Dr. Mager is Professor of Pharmaceutical Sciences at the University at Buffalo. He has served as Visiting Professor at the Université Paris Descartes and on the Advisory Committee on Clinical Pharmacology to the FDA. His research invokes PK/PD systems analysis with particular interest in anti-cancer and immunomodulatory pharmacotherapy.
|08:30-08:45||Dr. W.J. Jusko: Introductions|
|08:45-09:45||Dr. W.J. Jusko: Overview of PK/PD|
|09:45-10:45||Dr. D. Mager: Art of Modeling|
|11:00-12:00||Dr. D. Mager: Basic Pharmacology|
|01:00-02:00||Dr. W.J. Jusko: Modeling Biophase Distribution|
|02:00-03:00||Dr. W.J. Jusko: Basic Indirect Response Models|
|03:15-04:15||Dr. D. Mager: Modeling Transduction Processes|
|04:15-05:00||Dr. W.J. Jusko: Slow & Irreversible Effects|
|08:30-09:45||Dr. D. Mager: Review & Exercises I|
|10:00-11:00||Dr. W.J. Jusko: Chemotherapy Models|
|11:00-12:00||Dr. W.J. Jusko: Indirect Response Complexities|
|01:00-02:00||Dr. W.J. Jusko: Modeling Tolerance Processes|
|02:00-03:00||Dr. D. Mager: Target-Mediated PK/PD Models|
|03:15-04:15||Dr. W.J. Jusko : Modeling Drug Interactions|
|04:15-05:15||Pf. J. Fiedler-Kelly: Population PK/PD Models|
|08:30-09:45||Dr. W.J. Jusko: Review & Exercises II|
|10:00-11:00||Dr. D. Shah: PKPD Monoclonal Antibodies|
|11:00-12:00||Dr. W.J. Jusko: Disease Progression Models|
|01:00-02:00||Dr. D. Mager: Species Scaling in PKPD|
|02:00-03:00||Dr. J. Earp: FDA & Pharmacometrics|
|03:15-04:15||Dr. D. Mager: Systems Modeling in PK/PD|
|04:15-04:30||Dr. W.J. Jusko: Final Discussion and Summary|
Individual fee: $2,800. This includes course documentation, continental breakfasts, mid-session refreshments, lunches and opening dinner. Up to 5 graduate students may enroll at a fee of $1,400 (registered MS and PhD).
Cancellations with a full refund may be made until March 12, 2019. No refunds will be given for cancellations received after this date. Substitutions may be made at any time.
The course will be held at:
The Conference and Event Center Niagara Falls
101 Old Falls Street
Niagara Falls, NY 14303, USA
Phone: (716) 278-2100
Fax: (716) 278-0008
The Conference Center is 28 minutes from the Buffalo Niagara International Airport.
Sheraton at the Falls
300 Third Street
Niagara Falls, NY 14303, USA
Phone: (716) 285-3361.
The price is $93/night single and double occupancy (add $10 per person for triple and quadruple occupancy).
Hotel deadline: April 8, 2019
Contact UB course secretary Suzette Mis at (716) 645-4831 or email@example.com if you need assistance.