Youngjae You PhD

Youngjae You

Youngjae You

Professor of Empire Innovation

Department of Pharmaceutical Sciences

School of Pharmacy

Specialty/Research Focus

Antibody-Drug Conjugates; Cancer Chemotherapy; Drug Delivery; Medicinal Chemistry; Targeted Drug Delivery

Contact Information
630 Pharmacy Building
Buffalo, NY 14214-8033
Phone: (716) 645-4843

Education and Training:

  • PhD, Pharmaceutical Chemistry, Chungnam National University (2001)
  • MS, Pharmaceutical Chemistry, Chungnam National University (2000)
  • BPharm, Chungnam National University (1994)


  • Professor, Pharmaceutical Sciences, University at Buffalo (2019-present)
  • Adjunct Professor, Biochemistry & Molecular Biology, University of Oklahoma Health Sciences Center, College of Medicine (2019)
  • Professor, Pharmaceutical Sciences, University of Oklahoma Health Sciences Center (2018–2019)
  • Adjunct Professor, Peggy and Charles Stephenson School of Biomedical Engineering, Universtiy of Oklahoma, Gallogly College of Engineering (2018–2019)
  • Investigator, Peggy and Charles Stephenson Oklahoma Cancer Center (2011–2019)
  • Associate Professor, Pharmaceutical Sciences, Univesity of Oklahoma Health Sciences Center (2010–2018)
  • Adjunct Associate Professor, Chemistry and Biochemistry, University of Oklahoma (2010–2018)
  • Assistant Professor, Chemistry and Biochemistry, South Dakota State University (2006–2010)
  • Research Assistant Professor, Chemistry, University at Buffalo (2004–2006)
  • Post Doctoral Fellow, Chemistry, University at Buffalo (2001–2004)
  • Pharmacist, Dok-il Community Pharmacy, Korea, Republic Of (1995)
See all (1 more)

Awards and Honors:

  • Professor of Empire Innovation, University at Buffalo (2019)
  • PHF Presidential Professorship, OUHSC (2018)
  • Idea Award with Special Focus, Peer Reviewed Cancer Research Program (CDMRP, DOD) (2016)
  • Idea Expansion Award, Breast Cancer Research Program (CDMRP, DOD) (2014)
  • Research Scholar Grants Award, American Cancer Society (2013)
  • Breast Cancer Seed Grant: Stephenson Cancer Center (2011)
  • Idea Award, Breast Cancer Research Program (CDMRP, DOD) (2008)
  • Research/Scholarship Support Award, SDSU (2007)
  • Research/Scholarship Support Award for New faculty, SDSU (2006)
  • Postdoctoral Fellowship Award, Breast Cancer Research Program (CDMRP, DOD) (2003)
  • Health Science Fellowship - Korean Health Science Foundation (1996)

Research Expertise:

  • Pharmaceutical Chemistry & Drug Delivery: Pharmaceutical Chemistry, Drug Delivery, Photodynamic Therapy, Photochemistry, PK/PD Modeling

Grants and Sponsored Research:

  • July 2022–June 2027
    Singlet Oxygen-cleavable Prodrugs for Treating Non-Muscle Invasive Bladder Cancers
    National Cancer Institute/ NIH
    Role: Principal Investigator
  • September 2018–August 2021
    Mechanistic Studies of gamma-Glutamyl Transpeptidase inhibition: a Novel Approach to Modulating Serum Levels of Cysteine
    Role: Co-Investigator
  • August 2017–July 2020
    Visible Light-Controlled Combination Strategy for Treating Nonmuscle Invasive Bladder Cancers
    Role: Principal Investigator
  • March 2015–January 2020
    NIR-activatable Prodrugs for Treating Peritoneally Metastasized Ovarian Cancers
    Role: Principal Investigator
  • September 2014–September 2017
    A Synergistic Combination Therapy of Photodynamic Therapy and Chemotherapy for Breast Cancer
    Role: Principal Investigator
  • July 2016–June 2017
    Administrative Supplement for purchasing 300 MHz NMR system
    Role: Principal Investigator
  • July 2013–June 2016
    Fluorescence Cystoscopy-Photodynamic Therapy for Early Bladder Cancers
    American Cancer Society
    Role: Principal Investigator
  • September 2012–August 2013
    Identifying the DRUG target in dormant cancer cells
    Role: Co-Investigator
  • February 2009–September 2012
    Targeted Delivery and Remote-Controlled Release of Chemotherapeutic Agents
    Role: Principal Investigator


  • BODIPY derivatives and methods of synthesis and use thereof (2017)
  • Singlet oxygen-labile linkers and methods of production and use thereof (2016)

Journal Articles:

See all (12 more)

Books and Book Chapters:

  • You Y. Heteroatom-substituted dioxetanes and their emerging biomedicalapplications. 2014.

Professional Memberships:

  • International Society for Optics and Photonics (SPIE) (2019–present)
  • American Society for Pharmacology and Experimental Therapeutics (2016–present)
  • American Associate of College of Pharmacy (2010–present)
  • American Society for Photobiology (2006–present)
  • American Association of Pharmaceutical Scientists (2005–present)
  • American Association of Cancer Research (2005–present)
  • American Chemical Society (2002–present)
  • Pharmaceutical Society of Korea (1995–present)

School News:

In the Media:

Clinical Specialties:

Clinical Offices:

Insurance Accepted:

Contact Information

630 Pharmacy Building
Buffalo, NY 14214-8033
Phone: (716) 645-4843