Publications

  1. Campagne O, Mager DE, Brazeau D, Venuto RC, Tornatore KM. (2018) Tacrolimus Population Pharmacokinetics and Multiple CYP3A5 Genotypes in Black and White Renal Transplant Recipients. J Clin Pharmacol.  May 18, 2018; DOI: 10.1002/jcph.1118. [Epub ahead of print]   PMID:29775201
  2. Venuto RC, Meaney CJ, Chiang S, Leca N, Consiglio J, Wilding G, Brazeau D, Gundroo A, Morse SE, Nainani N, Cooper LM, Tornatore KM. (2015). Association of Extrarenal Adverse Effects of Post-Transplant Immunosuppression with Sex and ABCB1 Haplotypes. Medicine; 94(37); September 2015, p e1315; DOI: 10.1097/MD.0000000000001315.
  3. Tornatore KM, Meaney CJ, Wilding GE, Chang SS, Gundroo A, Cooper LM, Gray V,Shin K, Fetterly GJ, Prey J, Clark K, Venuto RC. Influence of sex and race on mycophenolic acid pharmacokinetics in stable African American and Caucasian renal transplant recipients. Clin Pharmacokinet. 2015 Apr;54(4):423-34. doi:10.1007/s40262-014-0213-7. PubMed PMID: 25511793; PubMed Central PMCID:PMC4435744.
  4. Meaney CJ,  Arabi Z,  Venuto RC, Consiglio J, Wilding G, Tornatore KM: Validation and Reliability of a novel immunosuppressive adverse effects scoring system in renal transplant recipients; BMC Nephrology  2014; 15:88 (Epub: June 19, 2014); doi:10.1186/1471-2369-15-88.
  5. McGuire O, Tornatore KM, O’Loughlin KL, Venuto RC, Minderman H: Nuclear translocation of Nuclear Factor of Activated T cells (NFAT) as a quantitative pharmacodynamic parameter for tacrolimus; Cytometry A Cytometry A December 2013:83:1096-1104 (Epub: Oct 17, 2013); DOI: 10.1002/cyto.a.22401.
  6. Tornatore KM,  Brazeau D,  Dole K,, Danison RT,  Wilding G, Leca N, Gundroo A, Gillis K, Zack J, DiFrancesco R, Venuto RC: Sex Differences in Cyclosporine Pharmacokinetics  and ABCB1 Gene Expression in Mononuclear Blood Cells in African American and Caucasian Renal Transplant Recipients; Journal of Clinical Pharmacology; October 2013; 53(10); 1039-1047. (ePub: July 3, 2013) DOI: 10.1002/jcph.123. 
  7. Tornatore KM, Sudchada P, DiFrancesco RA, Attwood, K, Gundroo A, Gray V, Wilding G, Hochreitter, J, Venuto RC: Race and Drug Formulation Influence on Mycophenolic Acid and Metabolite Pharmacokinetics in Stable Renal Transplant Recipients. Journal of Clinical Pharmacology (Epub: January 24, 2013); March 2013: 53:3; 285-293 doi:10.1177/0091270012447814).   
  8. Kumar R, Pendyala P, Sudchada P, Venuto R, Gray V, Gundroo A, Attwood K, Wilding G, Tornatore K. Comparison of 12-hour creatinine clearance and estimated glomerular filtration rate in renal transplant recipients. Renal Failure (Epub 2013 Jan 29); 35(3): 333-7 1/2013. doi: 10.3109/0886022X.2012.757824. PMID: 23356545.
  9. Nainani N, Patel T, N, Kumar R, Weber-Shrikant E, Gundroo A,  Murray B, Tornatore K, Blessios G, Venuto R.  Effect of steroid free, low concentration calcineurin maintenance immunosuppression regimen on renal allograft histopathology and function.  Nephrology Dialysis Transplantation (accepted 5/2011); electronic version doi:10.1093/ndt/gfr608; 11/5/11; pg 1-7 PMID: 22058172. 
  10. Tornatore K, Sudchada P; DiFrancesco R, Wilding G, Dole K, Leca N, Gundroo A, Venuto RC; Mycophenolic Acid Pharmacokinetics during Maintenance Immunosuppression in African American and Caucasian Renal Transplant Recipients; Journal of Clinical Pharmacology  (electronic version: January 5, 2011 as doi:10.1177/0091270010382909); August 2011:51:8; 1213-1222 ; PMID: 21209244. 
  11. Damodar A, Mustafa R, Bhatnagar J, Panesar M, Gundroo A, Zachariah M, Blessios G, Tornatore KM,  Weber-Shrikant E, Venuto RC.  Use of Anti-CD20 Antibody in the treatment of Post-Transplant Glomerulonephritis.  Clinical Transplantation (Online Version of Record 4/2010); May/June: 25(3):375-379. PMID: 20384712. 
  12. Zachariah M, Tornatore KM; Venuto RC; Kidney Transplantation and pregnancy. Current Opinion in Organ Transplantation; 2009;14:386-391  PMID: 19512929. 
  13. Nainani N,  Singh N,  Shanahan T, Damodar A,  Parimoo N, Ummadi S,  Qazi Y, Murray BM,  Tornatore KM, Ciccirella JC, Blessios GA, Venuto RC. Cross Reactive Epitope Group Antibodies in Sensitized Kidneys Transplant recipients was associated with Early Acute Antibody Mediated Rejection.  Transplant Immunology  2009: 20: 113-117  PMID: 18996198. 
  14. DiFrancesco R , Frerichs V, Donnelly J, Hagler C, Hochreitter J, Tornatore KM. Simultaneous Determination of Cortisol, Dexamethasone, Methylprednisolone, Prednisone, Prednisolone, Mycophenolic Acid and Mycophenolic Acid Glucuronide in Human Plasma Utilizing Liquid Chromatography Tandem Mass Spectrometry. Journal of Chromatography B.  2007:859:42-51. PMID: 17928278.
  15. Qazi YA, Forrest A, Tornatore K, Venuto R. The Clinical Impact of 1:1 Conversion from Neoral to Generic Cyclosporine (Gengraft) in Renal Transplant Recipients with Stable Graft Function. Clinical Transplantation   2006; 20:313-317. PMID: 16824147. 
  16. Tornatore KM, Gilliland KA, Farooqui M, Reed KA, Venuto RC.  Pharmacokinetics and Pharmacodynamics of Methylprednisolone in Premenopausal Renal Transplant Recipients. Journal of Clinical Pharmacology  2004; 44:9:1003-1011. PMID:15317828. 
  17. Frerichs VA, Tornatore KM.  Determination of the Corticosteroids Prednisone, Prednisolone, Dexamethasone, and Cortisol in Human Serum and Plasma Using Liquid Chromatography Coupled to Tandem Mass Spectrometry.  Journal of Chromatography B 2003;802: 329-338.
  18. Tornatore KM, Garey KW, Saigal N, Reed K, Murray B, Ingalls E, DiFrancesco R, Forrest A, Morse G, Venuto R.  Ganciclovir Pharmacokinetics and Cytokine Dynamics in Renal Transplant Recipients with Cytomegalovirus Infection. Clin Transplantation 2001;15:297-308.  PMID: 11678955. 
  19. Tornatore KM, Logue G, Davis PJ: Longitudinal Study of Cortisol Pharmacodynamics and Methylprednisolone Pharmacokinetics in Healthy Elderly Males after Exposure to Glucocorticoids. Gerontology 1999; 110 - 116. 
  20. Tornatore KM, Venuto RC, Logue G, Davis PJ:  CD4+ and CD8+ Lymphocyte and Cortisol Response Patterns in Elderly and Young Males during Methylprednisolone Exposure.  Journal of Medicine 1998; 29(3-4):159-183. PMID: 9865456. 
  21. Tornatore KM, Logue G, Venuto RC, Davis PJ:  Cortisol Pharmacodynamics after Methylprednisolone Administration in Young and Elderly Males.  Journal Clinical Pharmacology 1997; 37:304-311. PMID: 9115056.  
  22. Tornatore KM, Reed KA, Venuto RC: Assessment of Methylprednisolone Pharmacokinetics and Cortisol Response during Early and Chronic Post renal-Transplant Periods.  Transplantation 1995; 60:1607-1611. 
  23. Tornatore KM, Reed K, Venuto RC:  24 Hour Assessment of CD4+ and CD8+ Lymphocytes in Renal Transplant Recipients Receiving Chronic Methylprednisolone. Clinical  Nephrol 1995;44:290-298. PMID: 8605708. 
  24. Tornatore KM, Reed KA, Venuto RC: Methylprednisolone and Cortisol Metabolism during the Early Post-Renal Transplant Period. Clinical  Transplantation 1995:9:427-432. PMID: 8645883. 
  25. Tornatore KM, Biocevich D, Reed K, Tousley K, Gray V, Singh J, Venuto R:  Post-transplant Diabetes Mellitus and Methylprednisolone Pharmacokinetics in Black and White Renal Transplant Recipients.  Clinical Transplantation 1995;9:289-296. PMID: 7579735. 
  26. Tornatore KM, Reed KA, Venuto RC:  Intrapatient Assessment of Chronic Methylprednisolone Pharmacokinetics in Renal Transplant Recipients.  Annals Pharmacotherapy 1995;29:120-4. 
  27. Tornatore KM, Reed KA, Venuto RC:  Pharmacokinetics of Methylprednisolone During Acute Renal Allograft Rejection.  Clin Transplantation 1995;9:74-78. PMID: 7599405
  28. Tornatore KM, Biocevich D, Reed KA, Tousley K, Singh P, Venuto R:  Methylprednisolone Pharmacokinetics, Cortisol Response, and Adverse Effects in Black and White Renal Transplant Recipients.  Transplantation 1995;59:729-736. PMID:7886801.  
  29. Tornatore KM, Reed KA, Venuto RC.  Repeated Assessment of Methylprednisolone Pharmacokinetics During Chronic Immunosuppression in Renal Transplant Recipients. Ann Pharmacotherapy 1995;20:120-124. PMID: 7756707. 
  30. Tornatore KM, Logue G, Venuto RC, Davis DJ:  Methylprednisolone Pharmacokinetics in Elderly and Young Healthy Males.  Journal  American Geriatric Society 1994;42:118-122. PMID: 7930339. 
  31. Tornatore KM, Walshe JJ, Venuto RC:  Cortisol Pharmacodynamic Response to Long-Term Methylprednisolone in Renal Transplant Recipients.  Pharmacotherapy 1994;14:111-118. 
  32. Tornatore KM, Reed KA, Venuto RC:  CD4+/CD8+ Lymphocyte Patterns in Renal Transplant Recipients Receiving Chronic Methylprednisolone.  Journal of Medicine 1993;24:98-112. PMID: 8605708.
  33. Tornatore KM, Reed KA, Venuto RC: Racial Differences in Pharmacokinetics of Methylprednisolone in Black and White Renal Transplant Recipients.  Pharmacotherapy 1993;13:481-486. PMID: 8247916 
  34. Tornatore KM, Holdsworth M, Walshe JJ, Venuto RC:  Comparative Pharmacokinetics of Methylprednisolone in Renal Transplant Recipients Receiving Triple or Double Drug Immunosuppression.  Annals Pharmacotherapy 1993;27:545-9. PMID: 8347899. 
  35. Tornatore KM, Morse GD, Jusko WJ, Walshe JJ:  Methylprednisolone Disposition in Renal Transplant Recipients Receiving Triple Drug Immunosuppression.  Transplantation, 1989;48:962 965. PMID: 2595785. 
  36. Kanarkowski R, Tornatore KM, D'Ambrosio R, Gardner MJ, Yurchak AM, Jusko WJ:  Pharmacokinetics of Single and Multiple Doses of Ethinyl Estradiol and Levonorgestrel in Relation to Smoking.  Clinical Pharmacology Therapeutics. 1988;43:23 31. PMID: 3121231.
  37. Kanarkowski  R, Tornatore KM, McCarthy TL, Gardner MJ, Yurchak AM, Jusko WJ:  Effects of Oral Contraceptive Use on Drug Disposition.  Zbl. Pharm., 1983;122:709 715. PMID: 1427996
  38. Gardner M, Tornatore KM, Jusko, WJ, Kanarkowski, R: Effects of Tobacco Smoking and Oral Contraceptive Use on Theophylline Disposition.  British Journal Clinical Pharmacology 1983;16:271 280. PMID: 6626419.
  39. Tornatore KM, Kanarkowski, R, McCarthy, TL, Gardner, MJ, Yurchak, AM, Jusko, WJ:  Effect of Chronic Oral Contraceptive Steroids on Theophylline Disposition.  European Journal Clinical Pharmacology 1982;23:129 134. PMID:  7140802.