School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, The State University of New York
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William J. Jusko
Pharmaceutical Sciences
Chair, Pharmaceutical Sciences, SUNY Distinguished Professor
565 Hochstetter Hall
Buffalo NY 14260
Phone: (716) 645-2855
Fax: (716) 645-3693

Website: http://pharmacy.buffalo.edu/phc/faculty/JSKO.HTML
Email: wjjusko@buffalo.edu


Research interests are in theoretical, basic, and clinical aspects of the pharmacokinetics and pharmacodynamics of various immunosuppressive agents including corticosteroids, as well as drugs used to treat diabetes, inflammation, and cancer. With Drs. Richard Almon and Debra DuBois, Dr. Jusko delves into the pharmacogenomics of diverse effects of corticosteroids and has evolved advanced mathematical models of receptor/gene-mediated responses. They have characterized the effects of corticosteroids on hepatic and muscle enzymes and tissue responses and have evolved advanced PK/PD models for cascade-type processes. Dr. Jusko has developed mechanism-based pharmacokinetic, pharmacodynamic, and disease progression models and computational methods describing the action of various drugs and utilizes mathematical models of drug action to determine optimal dosage regimens diverse drugs.
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