Graduated Fellows

  • Dr. Yanguang Cao
    Minimal PBPK models for monoclonal antibodies
  • Dr. Gary Mo
    Role of pharmacodynamic response in the clearance of drugs targeting membrane-bound receptors
  • Weiyan Zhang, PhD
    In vivo mechanisms of drug-load release for antibody drug conjugates (ADC) and their relationships to drug-related toxicity
  • Jie Zhao
    Distribution of Etanercept to Sites of Inflammation in Collagen-Induced Arthritic Rats
  • Frank Engler
    Evaluation of the influence of nephropathy on mAb disposition
  • Xi Chen
    Effects of inflammation on mAb pharmacokinetics and pharmacodynamics
  • Patrick Glassman, Ph.D. candidate
    PBPK model of mAb disposition: Inclusion of mAb-target pH-dependent dissociation and FcRn-mediated recycling
  • Tommy Li, Ph.D. candidate
    Effects of immunosuppressive therapy on human FcRn expression in transgenic mice
  • Veena Thomas
    Evaluation of mAb-receptor binding: Comparison of experimental methods and model-based inference
  • Anas Fathallah,
    Determining immunogenicity risk associated with product aggregation and route of administration
  • Jun Wang
    ‘Tumor priming’ to enhance mAb penetration in pancreatic cancer
  • Gurkishan Chada
    Effect of Type II diabetes mellitus and chronic kidney disease on antibody pharmacokinetics
  • Anita Moein
    Evaluation of mAb distribution to the brain: Non-invasive imaging vs. necropsy
  • Mark Bryniarski
    Absorption mechanisms of monoclonal antibodies following oral delivery protected by Cholestosomes(TM), using imaging of lymphatics to define absorption
  • Yang Chen
    Physiologically-based pharmacokinetic (PBPK) modeling of IgG
  • Qi (Nancy) Zhang, PhD
    PK/PD/PG/DIS Models for Etanercept Interactions with Cytokines in a Rat Model of RA
  • Shang-Chiung Chen, PhD
    Investigation of the influence of FcRn recycling on the target-mediated elimination of of anti-CEA monoclonal antibodies in mice
  • Xiaoyan Zhang, PhD
    Investigation of the influence of Fc-gamma-R on the elimination of monoclonal antibodies
  • John Harrold, PhD
    Multiscale Systems Analysis of Anti-CD20 mAb Pharmacodynamics
  • Leonid Kagan, PhD
    Interferon-beta Biodisposition and Effects on Osteolytic Lesions
  • Lubna Abuqayyas, PhD
    PBPK modeling of the disposition of non-targeted and targeted antibodies in SCID mice
  • Dr. Hoi Kei Lon
    Etanercept Pharmacokinetics in Collagen-Induced Arthritic Rats
  • Tao Ji, Ph.D.
    Use of accelerator mass spectrometry for investigating target ligand turnover kinetics
  • Bo Zheng, PhD
  • Alison Gaudy, PhD
    Influence of charged residues in the variable domain on half-life, tissue distribution, and bioavailability of therapeutic IgG antibodies
  • Meric Ovacik, PhD
    Algorithmic study design for identification of target expression from disposition data