Laboratory for Antimicrobial Pharmacodynamics

Our laboratory is focused on novel approaches to combat bacterial resistance by studying interdisciplinary areas including antimicrobial pharmacokinetics and pharmacodynamics, clinical pharmcology, bacterial genetics, and translational medicine.

Our philosophy is to blend cutting-edge modeling with strong clinical and translational science for efficient drug development.

We are located at the New York State Center of Excellence and Bioinformatics and collaborate with the investigators from the University at Buffalo School of Medicine, School of Pharmacy, Next Generation Sequencing Core, Roswell Park Cancer Institute, and the pharmaceutical industry.

We utilize a variety approaches to optimize the profile of new and existing antibiotics including susceptibility and bactericidal testing, the cutting edge hollow fiber infection model, and advanced pharmacometric analyses.