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MS: Focus in Pharmacometrics |
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What is Pharmacometrics?Studies in preclinical and clinical pharmacology, pharmacokinetics, pharmacodynamics, and toxicology typically involve collection of various types of experimental data in individual and groups of biologic preparations, animals, and human subjects.Appropriate methods of analysis of such data requires an understanding of the underlying science and well as use of biostatistics, computational methods, and pharmacokinetic and pharmacodynamic modeling. Scientists with proficiency in pharmacometrics can assist in the design and analysis of protocols and studies related to drug therapy questions and provide insights into the processes which control the time course of drug concentrations and clinical, pharmacologic and toxicologic responses. Purpose: To prepare graduates for industrial or other positions or for more advanced academic training in areas requiring computer-assisted analysis of biopharmaceutic, pharmacokinetic, pharmacodynamic, toxicologic, or other types of experimental data. Prerequisites: Calculus (e.g., MTH 141) and computer programming (eg. C++, Fortran, Visual Basic). Requirements: Enrollment in the Pharmaceutical Sciences Department and completion of 30 credits of academic work. It is expected that program completion will be within 1 yr. A. Required Courses (12 credits) F = Fall, S = Spring
C. PHC 616 (1-5) S Research. Completion of a research project under supervision or collaboration with a suitable graduate faculty member in the School of Pharmacy. This project must involve data analysis and modeling. A project report in the form of a manuscript must be submitted and, if convenient, presentation of a poster at a suitable forum. Supervision: One member of the Graduate Faculty of the School of Pharmacy will serve as Supervisor and two other faculty members will serve on the MS Committee. D. PHC 613, 614 (1,1) F,S. Seminar. Students will be expected to attend the regular weekly departmental seminar. Note: Students will be required to attend tutorials in use and applications of software such as Adapt II, Kinetica, WinNonMix, NonMem, and perhaps other programs. E. Examination. A final oral examination will be required at the end of the academic and research program. This will be administered by the student¹s MS Committee in tandem with the presentation and defense of the research project. Who should apply: Students interested in the computational aspects of pharmaceutical research would be well suited for the program. Applicants should have at least a Bachelors degree in Pharmaceutics, Pharmacy, Pharmacology, Biology, Chemistry, Biochemistry, Mathematics, Statistics, or another suitable discipline. Work and computer experience in a research or clinical laboratory will be a plus. How to apply: Students interested in obtaining the MS degree from the Department of Pharmaceutical Sciences can apply online through the department webpage. Inquiries about this program can be addressed to Dr. Murali Ramanathan (Director of Graduate Studies, murali@buffalo.edu), or Dr. William J. Jusko (Program Coordinator, wjjusko@acsu.buffalo.edu). Applications for Fall admission are accepted through February 15. Late applicants are considered on a space-available basis. Stipend availability: At this point, no stipend is available to support students in this program. However, there may be opportunities for either scholarship support or part-time employment in faculty laboratories or other local facilities. Tuition and fee information can be found here: http://src.buffalo.edu/studentaccount/tuition.shtml. |
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