Reaching Others

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Dr. Jun Qu
Pharmaceutical Sciences
Associate Professor
318  Kapoor Hall 
Buffalo NY 14214-8033
Phone: (716) 881-7513


Email: junqu@buffalo.edu

Website: http://www.acsu.buffalo.edu/~junqu/


 Research Overview

 

Research focus areas:

Proteomics and Pharmaceutical Analysis. Major research programs in the proteomic field involve

i) high-resolution and large-scale expression profiling of pathological proteomes (e.g. for cardiovascular diseases, colon cancer and infectious diseases) for the discovery of disease/therapeutic biomarkers by gel-free LC/MS methods;

ii) Sensitive identification, localization and quantification of post-translational modifications in complex proteomes, with the emphases on arginine methylation and phosphorylation. Novel anti-PTM-peptides capture procedure and alternating collision induced dissociation (CID)/electron transferring dissociation (ETD) are employed to obtain abundant PTM information;

iii) targeted quantification of regulatory, marker proteins for clinical study.

Dr. Qu’s lab possesses many state-of-the-art LC/MS instruments, including a high resolution/accuracy LTQ/Orbitrap XL with ETD, a highly sensitive TSQ Quantum Ultra EMR triple-quadrupole instrument, two ultra-high pressure nano-LC systems, and several HPLC instruments for pre-fraction and ion chromatography.

A number of key analytical advances have been developed by his lab that greatly enhanced the proteomic coverage, sensitivity and throughput for proteomic research. As for the Pharmaceutical Analysis of small-molecule drug/markers, Dr. Qu’s lab is focusing on the ultra-sensitive quantifications of drug, metabolites and endogenous markers (e.g. corticosteroids, di-hydroxyl-vitamin D metabolites, androgens, etc.) using a novel combination of selective enrichment and micro- or nano- LC/MS.

 

Limited Faculty Profile
 

Brief Statement of Experience

 

Click here for Pub Med Publications

 

RESEARCH

 

Published Intellectual Contributions

 

Journal Article, Academic Journal (Published February 2013 Peer-Reviewed/Refereed)

Fisk, J. C., Li, J., Wang, H., Aletta, J. M., Qu, J., & Read, L. K. (2013). Proteomic analysis reveals diverse classes of arginine methylproteins in mitochondria of trypanosomes. Mol. Cell. Proteomics, 12(2), 302-11.

 

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 8, 2013 Not Peer-Reviewed/Refereed)

Horakova, D., Zivadinov, R., Weinstock-Guttman, B., Havrdova, E., Qu, J., Tamaño-Blanco, M., Badgett, D., Tyblova, M., Bergsland, N., Hussein, S., Willis, L., Krasensky, J., Vaneckova, M., Seidl, Z., Lelkova, P., Dwyer, M. G., Zhang, M., Yu, H., Duan, X., Kalincik, T., & Ramanathan, M. (2013). Environmental Factors Associated with Disease Progression After the First Demyelinating Event: Results from the Multi-Center SET Study. PLOS One, 8(1).

 

Journal Article, Academic Journal (Published December 2012 Peer-Reviewed/Refereed)

Tu, C., Li, J., Bu, Y., Hangauer, D., & Qu, J. (2012). An ion-current-based, comprehensive and reproducible proteomic strategy for comparative characterization of the cellular responses to novel anti-cancer agents in a prostate cell model. J Proteomics, 77, 187-201.

 

Journal Article, Academic Journal (Published June 2012 Peer-Reviewed/Refereed)

Duan, X., Dai, L., Chen, S.-C., Balthasar, J. P., & Qu, J. (2012). Nano-scale liquid chromatography/mass spectrometry and on-the-fly orthogonal array optimization for quantification of therapeutic monoclonal antibodies and the application in preclinical analysis. Journal of Chromatography A, 1251, 63-73.

 

Journal Article, Academic Journal (Published May 2012 Peer-Reviewed/Refereed)

Jamesdaniel, S., Coling, D. E., Hinduja, S., Ding, D., Li, J., Cassidy, L., Seigel, G., Qu, J., & Salvi, R. (2012). Cisplatin-induced Ototoxicity Is Mediated by Nitroxidative Modification of Cochlear Proteins Characterized by Nitration of Lmo4. J Biol Chem, 287(22), 18674-86.

 

Journal Article, Academic Journal (Published May 2012 Not Peer-Reviewed/Refereed)

Duan, X., Abuqayyas, L., Dai, L., Balthasar, J. P., & Qu, J. (2012). High-throughput method development for sensitive, accurate, and reproducible quantification of therapeutic monoclonal antibodies in tissues using orthogonal array optimization and nano liquid chromatography/selected reaction monitoring mass spectrometry..

 

Journal Article, Academic Journal (Published February 2013)

J C Fisk, J Li, H Wang, J M Aletta, Jun Qu, & Laurie K Read "Proteomic analysis reveals diverse classes of arginine methylproteins in mitochondria of trypanosomes". Mol. Cell. Proteomics, vol. 12, pp. 302-11, February 2013.

 

Journal Article, Academic Journal (Published December 2012)

CJ Tu, J Li, YH Bu, D Hangauer, & Jun Qu "An ion-current-based, comprehensive and reproducible proteomic strategy for comparative characterization of the cellular responses to novel anti-cancer agents in a prostate cell model". J Proteomics, vol. 77, pp. 187-201, December 2012.

 

Journal Article, Academic Journal (Published June 2012)

Xiaotao Duan, Lipeng Dai, Shang-Chiung Chen, Joseph P Balthasar, & Jun Qu "Nano-scale liquid chromatography/mass spectrometry and on-the-fly orthogonal array optimization for quantification of therapeutic monoclonal antibodies and the application in preclinical analysis". Journal of Chromatography A, vol. 1251, pp. 63-73, June 2012.

 

Journal Article, Academic Journal (Published May 2012)

S Jamesdaniel, Donald E Coling, Sneha Hinduja, Dalian Ding, Jun Li, Linda Cassidy, Gail Seigel, Jun Qu, & Richard Salvi "Cisplatin-induced Ototoxicity Is Mediated by Nitroxidative Modification of Cochlear Proteins Characterized by Nitration of Lmo4". J Biol Chem, vol. 287, pp. 18674-86, May 2012.

 

Journal Article, Academic Journal (Revising to Resubmit May 10, 2012)

Christopher A Jackson, Neelu Yadav, Sangwon Min, Jun Li, Eric J Milliman, Jun Qu, Yin-Chu Chen, & Michael C Yu "Proteomic Analysis of Interactors for Yeast Protein Arginine Methyltransferase Hmt1 Reveals Novel Substrate and Insights into Additional Biological Roles". Proteomics, May 10, 2012.

 

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 8, 2013)

Report Generated on February 21, 2013 Page 8 of 24 D Horakova, R Zivadinov, B Weinstock-Guttman, E Havrdova, Jun Qu, M Tamaño-Blanco, D Badgett, M Tyblova, N Bergsland, S Hussein, L Willis, J Krasensky, M Vaneckova, Z Seidl, P Lelkova, M G Dwyer, M Zhang, H Yu, X Duan, T Kalincik, & Murali Ramanathan "Environmental Factors Associated with Disease Progression After the First

Demyelinating Event: Results from the Multi-Center SET Study". PLOS One, vol. 8, January (1st Quarter/Winter) 8, 2013.

 

Journal Article, Academic Journal (Published May 2012)

X Duan, Lubna Abuqayyas, L Dai, Joseph P Balthasar, & Jun Qu. High-throughput method development for sensitive, accurate, and reproducible quantification of therapeutic monoclonal antibodies in tissues using orthogonal array optimization and nano liquid chromatography/selected reaction monitoring mass spectrometry., May 2012.

 

Journal Article, Academic Journal (Accepted February 7, 2013)

R Zivadinov, C N Treu, B Weinstock-Guttman, C Turner, N Bergsland, K O'Connor, M GDawyer, E Carl, D P Ramasamy, Jun Qu, & Murali Ramanathan "Interdependence and contributions of sun exposure and vitamin D to MRI measures in multiple sclerosis". J Neurol Neurosurg Psychiatry, February 7, 2013.

 

Abstract (Accepted February 2, 2012)

Eslam Nouri-Nigjeh, Jun Li, Haoying Yu, Siddharth Sukumaran, Debra C. Dubois, Richard R. Almon, William J. Jusko, & Jun Qu Extensive, Proteome-Level Investigation of the Corticosteroid Pharmacodynamics with 12 Time Points Using a Reproducible and Comprehensive Ion-Current-Based Profiling Strategy. 2012.

 

Journal Article, Academic Journal (Published May 23, 2011)

Zimmer, S., M. McEvoy, S., Li, J., Qu, J., & Read, L. (2011). A Novel Member of the RNase D Exoribonuclease Family Functions in Mitochondrial Guide RNA Metabolism in Trypanosoma brucei. J Biol Chem., 286(12), 10329-40.

 

Journal Article, Academic Journal (Published December 1, 2010)

Duan, x., Engler, F., & Qu, J. (2010). Electron transfer dissociation coupled to an Orbitrap analyzer may promise a straightforward and accurate sequencing of disulfide-bridged cyclic peptides: a case study.. J Mass Spectrom, 45(12), 1477-82.

 

Journal Article, Academic Journal (Published August 15, 2010)

song, w., Wang, Y., Yu, Z., . Rivera Vera, C. I., Qu, J., & Lin, Q. (2010). A metabolic alkene reporter for spatiotemporally controlled imaging of newly synthesized proteins in Mammalian cells.. ACS Chem Biol., 5(9), 875–885.

 

Journal Article, Academic Journal (Published June 1, 2010)

Qu, J., Lesse, A. J., Brauer, A. L., Cao, J., Gill, S. R., & Murphy, T. F. (2010). Proteomic expression profiling of Haemophilus influenzae grown in pooled human sputum from adults with chronic obstructive pulmonary disease reveal antioxidant and stress responses. BMC Microbiology, 10, 162.

 

Journal Article, Academic Journal (Published May 29, 2010)

Duan, X., Weinstock-Guttman, B., Wang, H., Bang, E., Li, J., Ramanathan, M., & Qu, J. (2010). Ultrasensitive quantification of serum vitamin D metabolites using selective solid-phase extraction coupled to microflow liquid chromatography and isotope-dilution mass spectrometry. Analytical Chemistry, 82(6), 2488-2497.

 

Journal Article, Academic Journal (Published February 15, 2010)

Weinstock-Guttman, B., Zivadinov, R., Qu, J., Cookfair, D., Duan, X., Bang, E., Bergsland, N., Hussein, S., Cherneva, M., Willis, L., Heinnen-Brown, M., & Ramanathan, M. (2010). Vitamin D metabolites are associated with clinical and MRI outcomes in multiple sclerosis patients. Journal of Neurology Neurosurgery Psychiatry, 82, 189-195.

 

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 2010)

Cao, J., Gonzalez-Covarrubias, V., Straubinger, R. M., Wang, H., Duan, X., Yu, H., Qu, J., & Blanco, J. G. (2010). A rapid, reproducible, on-the-fly orthogonal array optimization method for targeted protein quantification by LC/MS and its application for accurate and sensitive quantification of carbonyl reductases in human liver. Analyt. Chem., 82(7), 2680-9.

 

Journal Article, Academic Journal (Published November 2009)

Lee, M.-H., Koria, P., Qu, J., & Andreadis, S. (2009). JNK phosphorylates β-catenin and regulates adherens junctions. The FASEB Journal, 23(11), 3874+3883.

 

Journal Article, Academic Journal (Published August 1, 2009)

Vagin, V. V., Wohlschlegel, J., Qu, J., Jonsson, Z., Huang, X., Chuma, S., Girard, A., Sachidanandam, R., & Hannon, G. J. (2009). Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction withTudor family members. GENES & DEVELOPMENT, 23(15), 1749-1762.

 

Journal Article, Academic Journal (Published June 8, 2009)

Duan, X. T., Young, R., Straubinger, R. M., Page, B. J., Cao, J., Wang, H., Yu, H., Canty, J. M., & Qu, J. (2009). A straightforward and highly efficient precipitation/on-pellet digestion procedure coupled to long gradient nano-LC separation and Oribtrap mass spectrometry for the label-free expression profiling of swine heart mitochondria proteome. J. Proteome Res., 8(6), 2838-50.

 

Journal Article, Academic Journal (Published March 20, 2009)

Wang, H., Straubinger, R. M., Aletta, J. M., Cau, J., Duan, X. T., Yu, H., & Qu, J. (2009). Accurate localization and relative quantification of arginine methylation using nanoflow liquid chromatography coupled to electron transfer dissociation and orbitrap mass spectrometry. J Am Soc Mass Spectrom, 20, 507-519.

 

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 2009)

Yu, A., Qu, J., Felmlee, M. A., Cao, J., & Jiang, X.-L. (2009). Quantitation of human cytochrome P450 2D6 protein with immunoblot and mass spectrometry analysis. Drug Metab Dispos, 37(1), 370-377.

 


Presentations Given

 

Poster Presentation (Academic Peer-Reviewed)

Jusko, W. J., Sukumaran, S., Nouri-Nigjeh, E., Li, J., Yu, H., Dubois, D. C., Almon, R. R., & Qu, J. (2012, October). Proteome-level Pharmacokinetic/Pharmacodynamic Analysis of Corticosteroid-responsive Proteins in Rat Liver. Poster presented at the 2012 AAPS Annual Meeting and Exposition, Chicago, IL.

 

Poster Presentation (Academic Peer-Reviewed)

Qu, J., Shen, X., Jiang, X., Li, J., & Tu, C. (2012, September). Clinical investigation of potential biomarkers for innate HIV-1 virus control in long-term-non-progressing patients using a comprehensive and reproducible ion-current-based proteomic expression profiling. Poster presented at the HUPO 2012 11th Annual World Congress, Boston, MA.

 

Poster Presentation (Academic Peer-Reviewed)

Qu, J., Tu, C., Li, J., & Wilfrido, M. (2012, September). Comparative proteomic analysis of isolated colon cancer cells from multiple patients using a comprehensive ion current based approach. Poster presented at the HUPO 2012 11th Annual World Congress, Boston, MA.

 

Poster Presentation (Academic Peer-Reviewed)

Qu, J., Tu, C., Li, J., & Shen, X. (2012, September). Differential proteomic profiling of bronchoalveolar lavage fluid (BALF) for biomarker discovery in COPD. Poster presented at the HUPO 2012 11th Annual World Congress, Boston, MA.

 

Poster Presentation (Academic Peer-Reviewed)

Qu, J., Li, J., & Wang, H. (2012, September). An innovative dual-enzyme and dual-activation strategy for comprehensive and accurate characterization of protein arginine-methylation in Trypanosoma brucei. Poster presented at the HUPO 2012 11th Annual World Congress, Boston, MA.

 

Poster Presentation (Academic Peer-Reviewed)

Qu, J., Nouri-Nigjeh, E., Li, J., Yu, H., Sukumaran, S., Dubois, D. C., Almon, R. R., & Jusko, W. J. (2012, September). Extensive, proteome-level investigation of the corticosteroid pharmacodynamics with 12 time points using a reproducible and comprehensive ion-current-based profiling strategy. Poster presented at the HUPO 2012 11th Annual World Congress, Boston, MA.

 

Poster Presentation (Academic Peer-Reviewed)

Qu, J., Tu, C., Bu, Y., Yu, H., Li, J., & Hangauer, D. (2012, September). Investigation of the action mechanisms of new anti-carcinoma agents via high-resolution, comparative analysis of the drug-responsive proteomic signatures. Poster presented at the HUPO 2012 11th Annual World Congress, Boston, MA.

 

Poster Presentation (Academic Peer-Reviewed)

Qu, J., Tu, C., & Li, J. (2012, May). Biomarker discovery in chronic obstructive pulmonary disease: comparative proteome analysis of bronchoalveolar-lavage-fluid using a comprehensive and reproducible ion-current-based method. Poster presented at the 60th ASMS conference on Mass Spectrometry and Allied Topics, vancouver, BC.

 

Poster Presentation (Academic Peer-Reviewed)

Qu, J., Jiang, X., & Li, J. (2012, May). Identification of Novel HIV-invasion-markers by Comparing Long-term-non-progressor vs. Normal-progressors among HIV-infected patients using comprehensive and reproducible ion-current-based proteomic expression profiling. Poster presented at the 60th ASMS conference on Mass Spectrometry and Allied Topics, Vancouver, BC.

 

Poster Presentation (Academic Peer-Reviewed)

Qu, J., Duan, X., Wang, J., Li, L., & Balthasar, J. P. (2012, May). Characterization of the Kinetics of Therapeutic Antibody Immune Complexes In Vivo Using Blue Native Electrophoresis and Targeted Nano-LC/MS Analysis. Poster presented at the 60th ASMS conference on Mass Spectrometry and Allied Topics, Vancouver, BC.

 

Conference Presentation (Academic Peer-Reviewed)

Qu, J. (2012, May). Extensive, Proteome-Level Investigation of the Corticosteroid Pharmacodynamics with 12 Time Points Using a Reproducible and Comprehensive Ion-Current-Based Profiling Strategy. Paper presented at the 60th ASMS conference on Mass Spectrometry and Allied Topics, Vancouver, BC.

 

Keynote Presentation (Academic Invited)

Qu, J., Zhang, M., Dai, L., & Yu, H. (2012, May). Ultrasensitive, high-throughput and Robust Quantification of monoclonal antibodies in tissues and plasma using a novel Trapping-micro-LC/MS strategy and OAO optimization. Keynote presentation at the 60th ASMS conference on Mass Spectrometry and Allied Topics, Vancouver, BC.

 

Jusko, W. J., Sukumaran, S., Nouri-Nigjeh, E., Li, J., Yu, H., Dubois, D. C., Almon, R. R., & Qu, J. (2012, October). Proteome-level Pharmacokinetic/Pharmacodynamic Analysis of Corticosteroid-responsive Proteins in Rat Liver. Poster presented at the 2012 AAPS Annual Meeting and Exposition, Chicago, IL.

 

Qu, J., Shen, X., Jiang, X., Li, J., & Tu, C. (2012, September). Clinical investigation of potential biomarkers for innate HIV-1 virus control in long-term-non-progressing patients using a comprehensive and reproducible ion-current-based proteomic expression profiling. Poster presented at the HUPO 2012 11th Annual World Congress, Boston, MA.

 

Qu, J., Tu, C., Li, J., & Wilfrido, M. (2012, September). Comparative proteomic analysis of isolated colon cancer cells from multiple patients using a comprehensive ion current based approach. Poster presented at the HUPO 2012 11th Annual World Congress, Boston, MA.

 

Qu, J., Tu, C., Li, J., & Shen, X. (2012, September). Differential proteomic profiling of bronchoalveolar lavage fluid (BALF) for biomarker discovery in COPD. Poster presented at the HUPO 2012 11th Annual World Congress, Boston, MA.

 

Qu, J., Li, J., & Wang, H. (2012, September). An innovative dual-enzyme and dual-activation strategy for comprehensive and accurate characterization of protein arginine-methylation in Trypanosoma brucei. Poster presented at the HUPO 2012 11th Annual World Congress, Boston, MA.

 

Qu, J., Nouri-Nigjeh, E., Li, J., Yu, H., Sukumaran, S., Dubois, D. C., Almon, R. R., & Jusko, W. J. (2012, September). Extensive, proteome-level investigation of the corticosteroid pharmacodynamics with 12 time points using a reproducible and comprehensive ioncurrent- based profiling strategy. Poster presented at the HUPO 2012 11th Annual World Congress, Boston, MA.

 

Qu, J., Tu, C., Bu, Y., Yu, H., Li, J., & Hangauer, D. (2012, September). Investigation of the action mechanisms of new anti-carcinoma agents via high-resolution, comparative analysis of the drug-responsive proteomic signatures. Poster presented at the HUPO 2012 11th Annual World Congress, Boston, MA.

 

Report Generated on February 21, 2013 Page 5 of 12 Qu, J., Tu, C., & Li, J. (2012, May). Biomarker discovery in chronic obstructive pulmonary disease: comparative proteome analysis of bronchoalveolar-lavage-fluid using a comprehensive and reproducible ion-current-based method. Poster presented at the 60th ASMS conference on Mass Spectrometry and Allied Topics, vancouver, BC.

 

Qu, J., Jiang, X., & Li, J. (2012, May). Identification of Novel HIV-invasion-markers by Comparing Long-term-non-progressor vs. Normal-progressors among HIV-infected patients using comprehensive and reproducible ion-current-based proteomic expression profiling. Poster presented at the 60th ASMS conference on Mass Spectrometry and Allied Topics, Vancouver, BC.

 

Qu, J., Duan, X., Wang, J., Li, L., & Balthasar, J. P. (2012, May). Characterization of the Kinetics of Therapeutic Antibody Immune Complexes In Vivo Using Blue Native Electrophoresis and Targeted Nano-LC/MS Analysis. Poster presented at the 60th ASMS conference on Mass Spectrometry and Allied Topics, Vancouver, BC.

 

Qu, J. (2012, May). Extensive, Proteome-Level Investigation of the Corticosteroid Pharmacodynamics with 12 Time Points Using a Reproducible and Comprehensive Ion- Current-Based Profiling Strategy. Paper presented at the 60th ASMS conference on Mass Spectrometry and Allied Topics, Vancouver, BC.

 

Qu, J., Zhang, M., Dai, L., & Yu, H. (2012, May). Ultrasensitive, high-throughput and Robust Quantification of monoclonal antibodies in tissues and plasma using a novel Trappingmicro- LC/MS strategy and OAO optimization. Keynote presentation at the 60th ASMS conference on Mass Spectrometry and Allied Topics, Vancouver, BC.

 

Conference Presentation (Academic, peer-reviewed)

Qu, Jun (Author), Straubinger, Robert (Author), 2011 American Society for Mass Spectrometry annual meeting, "Investigation of the effect of cocaine use and withdrawal in rat models using comprehensive and reproducible ion-current-based proteomic expression profiling", Denver, CO. (Published in Proceedings: Yes).

 

Poster Presentation (Academic, peer-reviewed)

Qu, Jun, 2011 American Society for Mass Spectrometry annual meeting, "Large-scale comparative proteomic analysis of isolated colon cancer cells from multiple patients using a comprehensive and reproducible ion-current-based method", Denver, CO. (Published in Proceedings: Yes).

 

Poster Presentation (Academic, peer-reviewed)

Qu, Jun, 2011 American Society for Mass Spectrometry annual meeting, "Molecular-level elucidation of the anti-carcinoma mechanisms of new agents via high-resolution, comparative analysis of the drug-responsive proteomic signatures", Denver, CO. (Published in Proceedings: Yes).

 

Poster Presentation (Academic, peer-reviewed)

Qu, Jun, 2011 American Society for Mass Spectrometry annual meeting, "Retina Proteome Profiling in a Rat Model of Smith-Lemli-Opitz Syndrome Using a comprehensive, precise and reproducible Ion-current-Based Method", Denver, CO. (Published in Proceedings: Yes).

 

Poster Presentation (Academic, peer-reviewed)

Qu, Jun, 2011 American Society for Mass Spectrometry annual meeting, "An innovative dual-enzyme and dual-activation strategy for comprehensive and accurate characterization of protein arginine-methylation in Trypanosoma brucei.", Denver, CO. (Published in Proceedings: Yes; ).

 

Conference Presentation (Academic, invited)

Qu, Jun, 2011 American Society for Mass Spectrometry annual meeting, "accelerated Method Development for Sensitive, Accurate and Reproducible Quantification of Therapeutic Monoclonal Antibodies in Various Tissues Using Orthogonal-array-optimization and Nano-LC/SRM-MS", Denver, CO. (Published in Proceedings: Yes; ).

 

Poster Presentation (Academic, peer-reviewed)

Qu, Jun (Author), 2011 American Society for Mass Spectrometry annual meeting, "An ion-overfilling approach that significantly improves the sensitivity of Orbitrap and application in highly sensitive and accurate proteomic profiling", Denver, CO. (Published in Proceedings: Yes).

 

Poster Presentation (Academic, peer-reviewed)

Qu, Jun, 2011 American Society for Mass Spectrometry annual meeting, "An ion-overfilling approach that significantly improves the sensitivity of Orbitrap and application in highly sensitive and accurate proteomic profiling", Denver, CO. (Published in Proceedings: Yes).

 

Lecture (Academic)

Qu, Jun, "Cutting edge LC/MS-based method for investigation of Ophthalmological proteome", VA hospital, Buffalo, NY.

 

Keynote Presentation (Non-Academic, invited)

Qu, Jun, "The Delaware Valley DRUG METABOLISM DISCUSSION GROUP Symposium", "Accurate quantification and validation of therapeutic macromolecules", Philadelphia, PA..

 

Conference Presentation (Academic, invited)

Qu, Jun, Buffalo Pharmaceutical Syposium, "Ultra-sensitive quantification of therapeutic proteins", Buffalo, NY. (Published in Proceedings: No).

 

Conference Presentation (Academic, invited)

Qu, Jun, "Targeted investigation of mAB by nano-LC/MS/MS", Buffalo, NY. (Published in Proceedings: No).

 

Poster Presentation (Academic, peer-reviewed)

Qu, Jun, 2010 American Society for Mass Spectrometry annual meeting, "A high resolution, highly reproducible and sensitive nano_LC configuration that is particularly suitable for large-scale label-free expression profiling", Salt Lake City, UT. (Published in Proceedings: Yes).

 

Poster Presentation (Academic, peer-reviewed)

Qu, Jun, 2011 American Society for Mass Spectrometry annual meeting, "A comprehensive analysis of Swine Plasma Proteome Using Combinatorial Peptide Ligand Libraries (CPLL), Dual-Enzyme Digestion and Dual-Activation sequencing with LTQ/Orbitrap/ETD", Salt Lake City, UT. (Published in Proceedings: Yes).

 

Poster Presentation (Academic, peer-reviewed)

Qu, Jun, 2010 American Society for Mass Spectrometry annual meeting, "Exploring Cyclic Peptide Fragmentation by Electron Transfer Dissociation Coupled to Orbitrap Mass Spectrometry", Salt Lake City, UT. (Published in Proceedings: Yes).

 

Poster Presentation (Academic, peer-reviewed)

Qu, Jun, 2010 ASMS Anuual Meeting, "A rapid, reproducible, on-the-fly orthogonal array optimization method for targeted protein quantification by LC/MS and its application in clinical analysis", Salt Lake City, UT. (Published in Proceedings: Yes).

 

Poster Presentation (Academic, peer-reviewed)

Qu, Jun (Author), Straubinger, Robert, Blanco, Javier, 2010 ASMS Anuual Meeting, "A rapid, reproducible, on-the-fly orthogonal array optimization method for targeted protein quantification by LC/MS and its application in clinical analysis", Salt Lake City, UT. (Published in Proceedings: Yes).

 

Poster Presentation (Academic, peer-reviewed)

Morrow, Sarah (Author & Presenter), Ramanathan, Murali (Author), Benedict, Ralph (Author), Qu, Jun (Author), Duan, Xiatao (Author), Teter, Barbara (Author), Hojnacki, David (Author), Zivadinov, Robert (Author), Ramanathan, Murali (Author), American Academy of Neurology, "Vitamin D and cognitive impairment in multiple sclerosis (MS)", Toronto, ON, Canada. (Published in Proceedings: Yes; ).

 

Poster Presentation (Academic, peer-reviewed)

Weinstock-Guttman, Bianca (Author & Presenter), Zivadinov, Robert (Author), Qu, Jun (Author), Bang, Eunjin (Author), Hojnacki, David (Author), Munschauer, Frederick (Author), Bergsland, Niels (Author), Hussein, Sara (Author), Willis, Laura (Author), Cherneva, Mariya (Author), Ramanathan, Murali (Author & Presenter), American Academy of Neurology, "Vitamin D metabolites are linked to clinical and MRI outcomes in multiple sclerosis patients", Toronto, ON, Canada. (Published in Proceedings: Yes; ).

 

Poster Presentation (Academic, peer-reviewed)

Qu, Jun (Author), 239th National ACS Meeting, San Francisco, CA, March 22, 2010, "Photoaffinity labeling studies to better define the mechanism of action for Phase II oncology drug KX2-391 (KX01)", Francisco, CA. (Published in Proceedings: Yes).

 

Poster Presentation (Academic)

Fung, Ho Leung (Author), Tsou, Pei-Suen (Author & Presenter), Qu, Jun (Author), Experimental Biology 2009, "Identification Of Cysteine Residues In ALDH2 Responsible", FASEB, New Orleans.

 

 

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