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Pharmaceutical Sciences Department

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Founded by notable pioneers in the field of pharmaceutical sciences, including Gerhard Levy, Eino Nelson and Milo Gibaldi, the department has upheld a tradition of excellence over its half-century of existence. Our programs provide instruction and research training in diverse aspects of drug action including drug discovery to various elements of drug evaluation, examined at the molecular, genomic, biochemical, biological, and clinical levels through an interdisciplinary curriculum that is individualized to the needs of each incoming student. The program includes clinical and laboratory research focusing on pharmacokinetics, pharmacodynamics, dosage form design, physiochemical and biological aspects of drug action, drug metabolism, and drug toxicity.

 

The Pharmaceutical Sciences Program at UB SoPPS interdisciplinary fields of study that seek to achieve better understanding and control of the factors influencing clinical response to drug therapy. Its graduates continue to maintain leadership positions in academia, industry and government. The department is one of the largest of its kind, and is among the best funded (both by NIH and industry) in the country. Different to many PhD’s in other fields of science, our graduates are highly sought after for employment by industry, without the need for post-doctoral training. Graduates who prefer an academic career also find many offers of postdoctoral fellowships.

 

The Pharmaceutical Sciences combines an integrated knowledge of chemistry, biology, mathematics and computer sciences with human anatomy, physiology, biochemistry, disease and therapeutics to provide answers to: What dosage form or drug delivery system should be used? How much of a dose should be administered? How frequently should the dose be administered? Will the medication interact with other drugs? Should the dose be individualized based on age, body weight and composition, lifestyle factors, medical history, other diseases, and gene expression?

 

Areas of interest in Pharmaceutical Sciences include:

  • Physical Chemistry of pharmaceutical system: development and optimization of the physical/chemical properties of traditional and novel drug delivery systems;
  • Biopharmaceutics: the study of the relationship between the nature and intensity of biologic effects of drugs and various dosage form formulation factors;
  • Pharmacokinetics and Pharmacodynamics: the sciences of the quantitative analyses of drug concentrations and therapeutic effects, respectively, in the human body;
  • Clinical Pharmacokinetics and Clinical Pharmacodynamics: the application of pharmacokinetics and pharmacodynamics for safe and effective therapeutic patient management;
  • Pharmacogenomics and Bioinformatics: (1) how an individual's genotype governs his/her drug concentrations and therapeutic response; and (2) how drugs may alter a person's gene expression; and
  • Pharmacometrics: field that fuses pharmacology, computer sciences, mathematics and statistics to analyze diverse data in large populations of diverse patients.

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