New York State

Drug Disposal

Guides for Pharmacy Activities


In March 2010, the DA published a rule in the federal register dictating requirements for electronic prescribing and dispensing. This rule became effective June 1st, 2010. Amendments to Title 10 NYCRR Part 80 Rules and Regulations on Controlled Substances was adopted and became effective as final regulations on March 27, 2013. These regulations make the electronic prescribing of non-controlled substances and controlled substances mandatory as of March 27, 2015. Persons who prescribe and/or dispense controlled substances using e-prescriptions use a pharmacy application that meets the requirements set forth in 21 CFR part 1311.  The application must be approved by the  DEA certification organizations . Pharmacists are encouraged to check with their software vendors to make sure their computer system is in compliance with these regulations. Computer applications meeting federal security requirements must also be registered with the Department of Health’s Bureau of narcotic enforcement. If your computer application has met all federal security requirements you must register with the BNE by submitting an email and should include “Electronic Prescribing” in the subject as well as this pharmacy form  or practitioner form.

In addition, pharmacists are required to submit controlled substance data to Department of Health, Bureau of Narcotic Enforcement, using the American Society for Automation in Pharmacy (ASAP) format Version 4.2.