2011 December eNotes


University at Buffalo School of Pharmacy and Pharmaceutical Sciences
December 2011
Dean's e-Notes
Welcome to the December edition of eNotes.

This edition is our end-of-the-year overview where we showcase our students' professional and community-access programs, as well as other activities. Our next outreach to you will be our annual print newsletter, the "Buffalo Pharmacy Newsletter," which should be arriving in your mailboxes at the end of January. Our next edition of eNotes is targeted for March 2012. Please let me extend to you and your families my sincere wishes for a happy holiday season and much success in 2012!

Please stay in touch. Send us updates on your personal and professional accomplishments by email to phm-alumni@buffalo.edu.

With warm regards,
Wayne K. Anderson, PhD, professor and dean
Wayne Anderson, Ph.D., professor and dean
APhA Mid-year meeting
Students attending the meeting enjoyed getting to know each other at social events.
Students Host APhA-ASP Mid-Year Regional Meeting
The school's chapter of the American Pharmacists Association Academy of Student Pharmacists hosted the APhA-ASP Region 1 Mid-year Regional Meeting (MRM) Oct. 28-30 at the Buffalo Niagara Marriott. The weekend was filled with activities, with more than 200 attendees registered from 18 different schools. Associate Dean Karl Fiebelkorn and Jim Walsh, president of the Pharmacists Association of Western New York (PAWNY), kicked off the weekend with motivational speeches encouraging the use of networking opportunities and active involvement in student organizations. Attendees also took advantage of educational workshops on the residency match process, community outreach concerning prescription substance abuse, financial planning and more.

Another highlight of MRM was the policy process, during which student pharmacists voiced their opinions on what they would like to include in the upcoming APhA-ASP policy platform, based on current issues in the pharmacy profession. Lastly, attendees enjoyed social events focusing on the theme of Snow Day, including a chilled out Friday night White Out social and a Saturday night Wingfest, as well as the opportunity to meet new people and see old friends. Overall, the event was a success and the APhA-ASP chapter at UB was proud to serve as host and showcase UB and Western New York.

PharmD students conducted blood pressure screenings at UB's Wellfest.
Office of Experiential Education Hosts Outreach Events in Support of National Pharmacy Month
The Office of Experiential Education organized numerous student educational experiences, both in the community and on campus, in support of October's designation as "American Pharmacists Month" (APhM) recognizing the significant contributions to health care by pharmacists.

Bone density clinics were held at various Walgreens pharmacy locations throughout metro Buffalo. Sixty P2 and P3 students and Walgreens pharmacists conducted free bone density and blood pressure screenings, and counseled more than 100 patients. UB alumni and Walgreens pharmacists Karen Mlodezeniec, '91, regional district manager, and Stanley Piskorowski, '80, supervising pharmacist, helped organize the clinics. Read more.

Flu shot clinics also were held in the pharmacy school. Faculty, staff and students had the opportunity to receive free flu shots administered by our students under the supervision of faculty, residents and volunteer community pharmacists. Almost 200 PharmD students assisted with this immunization outreach project.

Pharmacy month activities concluded with students participating in UB's Wellfest. PharmD students conducted blood pressuring screenings, medication reviews and counseling for UB faculty, staff and students.

Dr. Erin Slazak, Pat Grace and Dr. Mark Wrobel represent faculty and staff at the 2011 Career Pathways Program.
Career Pathways Programs Prepare Students for Their Futures
Our annual Career Pathways program was held throughout October. This year's program was modified and enhanced to focus on P1-P2 career counseling during the alumni dinner on Oct. 18. The dinner featured alumni and community speakers discussing their career paths in such areas as the pharmaceutical industry, compounding and consultative pharmacy.

Other Career Pathways events included Patient Education Poster Presentations, during which 30 groups of P1 students presented their scholarly work on a variety of diseases state/patient education topics to faculty reviewers, and the Career Exhibition and Fair, where PharmD students met with a variety of local and regional pharmacies and other health care providers to discuss employment and other opportunities.

We would like to thank these generous sponsors for their support of our annual Career Pathways Program:

  • Rite Aid Pharmacy Management Lecture Fund
  • Bristol Myers/Westwood Lecture Fund in Pharmacy
  • UB Pharmacy and Pharmaceutical Sciences Alumni Association
  • UB School of Pharmacy and Pharmaceutical Sciences


Margaret Chrymko, '78 & '79
Margaret Chrymko, '78 & '79
Margaret Chrymko, '78 & '79, is the recipient of the 2011 Pharmacy Residency Excellence Preceptor Award from the American Society of Health-System Pharmacists Research and Education Foundation. Margaret is a clinical pharmacy specialist and residency program director for the Erie Veterans Affairs Medical Center in Pennsylvania, where she helped organize a national research design training program that is available to all VA residency programs.

In Memoriam:
James Johnson, '39
David Herr, '58

Javier Blanco
Cheng, Q.; Kalabus, J.L.; Zhang, J. & Blanco, J.G. A conserved antioxidant response element (ARE) in the promoter of human carbonyl reductase 3 (CBR3) mediates induction by the master redox switch Nrf2. Biochemical Pharmacology, 83, 139-148.


Donald Mager
Marathe, D.D., Marathe, A. & Mager, D.E. (2011). Integrated model for denosumab and ibandronate pharmacodynamics in postmenopausal women. Biopharmaceutics & Drug Disposition, 32, 471-481.

Gene Morse
Mudzviti T., Sibanda M., Gavi S., Maponga C.C. & Morse G.D. Implementing a pharmacovigilance program to evaluate cutaneous adverse drug reactions in an antiretroviral access program. Journal of Infection in Developing Countries. In press.

Brian Tsuji
Harigaya Y., Ngo D., Lesse A.J., Huang V. & Tsuji B.T. Characterization of heterogeneous vancomycin-intermediate resistance, MIC and accessory gene regulator (agr) dysfunction among clinical bloodstream isolates of staphyloccocus aureus. BMC Infect Dis. 2011 Oct. 25;11(1):287. [Epub ahead of print]
Tsuji B.T., MacLean R.D., Dresser L.D., McGavin M.J. & Simor A.E. Impact of accessory gene regulator (agr) dysfunction on vancomycin pharmacodynamics among Canadian community and health care associated methicillin-resistant Staphylococcus aureus. Ann Clin Microbiol Antimicrob. 10:20.
Miyazaki M., Takata T., Yoshimura H., Matsunaga A., Ohta D., Ishikura H., Futo M., Hara S., Kamimura H., Tamura K., Ngo D. & Tsuji B.T. Vancomycin bactericidal activity as a predictor of 30-day mortality in patients with methicillin-resistant Staphylococcus aureus bacteremia. Antimicrob Agents Chemother. 2011 April;55(4):1819-20. Epub 2011 Jan. 31.

Brian Tsuji and Alan Forrest
Butterfield J., Tsuji B., Brown J., Dodds Ashley E., Hardy D., Brown K., Forrest A. & Lodise T.P. Predictors of agr dysfunction in methicillin-resistant Staphylococcus aureus (MRSA) isolates among patients with MRSA bloodstream infections in the "15-20 mg/L" target vancomycin trough era. Antimicrob Agents Chemother. 2011 Sept. 19. [Epub ahead of print]
Bergen P.J., Tsuji B.T., Bulitta J.B., Forrest A., Jacob J., Sidjabat H.E., Paterson D.L., Nation R.L. & Li J. Synergistic killing of multidrug-resistant Pseudomonas aeruginosa at multiple inocula by colistin combined with doripenem in an in vitro PK/PD model. Antimicrob Agents Chemother. 2011 Sept. 12. [Epub ahead of print]
Bergen P.J., Forrest A., Bulitta J.B., Tsuji B.T., Sidjabat H.E., Paterson D.L., Li J. & Nation R.L. Clinically Relevant Plasma Concentrations of Colistin in Combination with Imipenem Enhance Pharmacodynamic Activity against Multidrug-Resistant Pseudomonas aeruginosa at Multiple Inocula. Antimicrob Agents Chemother. 55(11):5134-42. Epub 2011 Aug. 29.
Tsuji B.T., Okusanya O.O., Bulitta J.B., Forrest A., Bhavnani S.M., Fernandez P.B. & Ambrose P.G. Application of pharmacokinetic-pharmacodynamic modeling and the justification of a novel fusidic acid dosing regimen: raising Lazarus from the dead. Clin Infect Dis. 52 Suppl 7:S513-9.
Bulitta J.B., Landersdorfer C.B., Forrest A., Brown S.V., Neely M.N., Tsuji B.T. & Louie A. Relevance of Pharmacokinetic and Pharmacodynamic Modelling to Clinical Care of Critically Ill Patients. Curr Pharm Biotechnol. 2011 May 10. [Epub ahead of print]
Okusanya O.O., Tsuji B.T., Buelitta J.B., Forrest A., Bulik C.C., Bhavnani S.M., Fernandes P. & Ambrose P.G. Evaluation of the pharmacokinetics-pharmacodynamics of fusidic acid against Staphylococcus aureus and Streptococcus pyogenes using in vitro infection models: implications for dose selection. Diagn Microbiol Infect Dis. 2011 May;70(1):101-11.

Donald Mager
Mager, Donald (principal investigator), "Molecular and Clinical Pharmacology of Retinopathy of Prematurity." Sponsored by NIH, National Institutes of Health, $42,779.00. (9/30/11-6/30/16).

Gene Morse
G.D. Morse (PI) CFAR PI: S. Dewhurst, UR Developmental Center for AIDS Research, Translational TB Pharmacology Core NIH/NAID (11/1/11-4/30/13) ($355,955).

Nicole Albanese
Albanese, N. P. (2011, October). Navigating Diabetes Management in Elderly Patients. Paper presented at the NYSASCP, Buffalo, N.Y.

Kathleen Boje
Boje, K.M.K., & He, Y. (2011, October). Theoretical Physiologically Based Pharmacokinetic Simulations of Drug Brain Distribution: Implications of Intracarotid versus Systemic Administration for Brain Drug Delivery. Poster presented at the AAPS 2011 Annual Meeting.

Alice Ceacareanu
Ceacareanu, A.C., Hong, C.C., Nimako, G., Patel, K., Kossoff, E. & Forrest, A. (2011, September). Statin treatment use in diabetics with breast cancer: A potential C-reactive protein mediated benefit. Poster presented at the Breast Cancer Symposium 2011, San Francisco.

Patty Havard
Havard, P.F., Drozdowicz, M., Jaenecke, K., Tong, A., Franco, A., Ramirez, N., Barr, T., Beyer, W. & Brazeau, D. (2011, October). Aperio ImageScope algorithm: a more sensitive tool in detecting differences in IHC staining intensity of the placental vasculature as compared with visual scoring by a clinical pathologist. Poster presented at the 2011 ACCP Meeting.

William Jusko
Jusko, W.J., & He, Y. (2011, November). Population PK and PD Analysis of Oral Baclofen in Pediatric Patients with Cerebral Palsy. Paper presented at the Pediatric Neurology Cerebral Palsy Center, Washington University School of Medicine, St. Louis Children's Hospital.

Jusko, W.J., Sukumaran, S., Xue, B., Dubois, D.C. & Almon, R.R. (2011, October). Mechanistic Modeling of Tissue-specific Effects of Corticosteroids and Circadian Rhythms on Phosphoenolpyruvate Carboxykinase Expression in Rat Liver and Adipose Tissue. Poster presented at the 2011 AAPS Annual Meeting and Exposition.

Jusko, W.J., Cao, Y., Sun, H., Dubois, D.C. & Almon, R.R. (2011, October). Modeling Diabetes Disease Progression and Salsalate Intervention in Goto-Kakizaski Rats. Poster presented at the 2011 AAPS Annual Meeting and Exposition.

Jusko, W.J., Lon, H.K., Liu, D., Dubois, D.C. & Almon, R.R. (2011, October). Modeling Pharmacokinetics/Pharmacodynamics of Abatacept and Disease Progression in Collagen-induced Arthritic Rats--A Population Approach. Poster presented at the 2011 AAPS Annual Meeting and Exposition.

Jusko, W.J., Liu, D., Lon, H.K., Dubois, D.C. & Almon, R.R. (2011, October). Population Pharmacokinetic-Pharmacodynamic-Disease Progression Model for Effects of Anakinra in Lewis Rats with Collagen-induced Arthritis. Poster presented at the 2011 AAPS Annual Meeting and Exposition.

Jusko, W.J. (2011, October). The Relevance of Chronobiology in PK/PD. Paper presented at the 2011 AAPS Annual Meeting and Exposition.

William Jusko and Robert Straubinger
Jusko, W.J., Pawaskar, D., Straubinger, R.M. & Fetterly, G. (2011, October). Population Physiologically-based Pharmacokinetic Models for Everolimus and Sorafenib in Pancreatic Cancer Xenograft Mice. Poster presented at the 2011 AAPS Annual Meeting and Exposition.

Jusko, W.J., Ma, W.W., Pawaskar, D., Straubinger, R.M. & Fetterly, G. (2011, October). Systems Pharmacological Analysis of Molecularly Targeted Agents in Pancreatic Cancer: Pharmacodynamic Design of Novel Therapeutic Trails. Paper presented at the Clinical and Translational Research Colloquium, Buffalo Niagara Medical Campus.

Jusko, W.J., Pawaskar, D., Straubinger, R.M. & Fetterly, G. (2011, October). Population Physiologically-based Pharmacokinetic Models for Everolimus and Sorafenib in Pancreatic Cancer Xenograft Mice. Poster presented at the 2011 AAPS Annual Meeting and Exposition.

Gene Morse
Nanzigu, S., Lanke, S., Ma, Q. & Morse, G.D., A Physiological Pharmacokinetic Model Characterizes Efavirenz Metabolic Induction in HIV Infected Ugandan Patients. 2011 Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), September 2011.

Oramasionwu, C., Lawson, K., Brown, C.M., Koeller, J., Morse, G.D. & Frei, C., Use of Opportunistic Infection (OI) Prophylaxis between Blacks and Whites with HIV/AIDS. 2011 Infectious Diseases Society of America (IDSA), October 2011.

Scott Monte and Jerome Schentag
Monte S.V., Caruana J., Ghanim H., Schentag J.J. & Dandona P. Reduction in endotoxemia, oxidative and inflammatory stress, and insulin resistance following Roux-en-Y gastric bypass surgery in patients with morbid obesity and Type 2 diabetes mellitus. 71st Scientific Sessions American Diabetes Association.

Walter D. Conway, PhD, associate professor emeritus, Pharmaceutical Sciences, was honored with the dedication of a symposium issue of the Journal of Chromatography A (Sept. 9, 2011, vol. 1218) to recognize him for his lifetime of work in the field of counter-current chromatography (CCC). The issue is a compilation of papers, including one on theory and terminology authored by Conway and presented at the Sixth International Conference on CCC.
Assembly members Jane Corwin, Robin Schimminger and Crystal Peoples-Stokes.
PLAID Day Showcases Legislative and Public Policy Initiatives
Student leaders Christine Trezza, P3; Maria DiGuglielmo, P3; Sarah Farr, P2; Yi Yang, P2; Rebecca Campbell, P1; and Wesley Kufel, P1, again organized another successful Pharmacy Legislative Advocacy Invitational Day (PLAID). This year's session showcased New York State Assembly members Jane Corwin, Crystal Peoples-Stokes and Robin Schimminger. The lawmakers took part in a panel presentation that focused on various pharmacy-related public policy and legislative issues. Students were able to ask questions of the panel members.
Excellence in the Pharmaceutical Sciences Award Program
The Department of Pharmaceutical Sciences annually recognizes PharmD students who excel in pharmaceutical sciences-focused courses during the academic year. Ninety three P1, P2 and P3 students were recognized for their achievements in these courses during 2010-11. Professors Ramanathan, Straubinger, Mager and Blanco presented certificates of achievement to these students.


APhA-ASP Counseling Competition Announces First-Round Winners
Congratulations to the following top 10 winners of the first round of the American Pharmacists Association Academy of Student Pharmacists Counseling Competition: Nadia Aboley, Michael Bui, Tara Castleman, Jamie Chin, Sarah Farr, Arthur Fyles, Kyle Ma, Melek Turgut, Stephen Wolff and Tim Zablocki.

Each winner will receive textbook vouchers from APhA-ASP and a chance at the grand prize trip to New Orleans for the APhA national conference.

UB Team Places in Top Half of ACCP Clinical Pharmacy Challenge
The American College of Clinical Pharmacy held its annual clinical pharmacology competition. In this year's competition, 84 teams of three students each competed in a "quiz-bowl" format. Preliminary rounds were conducted "virtually" at the local level, with teams advancing through to the quarterfinal, semifinal and final rounds. Our UB team, consisting of P4 students Nicholas Bacon, Curtis Johnson and Aleksey Ushkin, made it to the third round of the virtual competition, placing UB in the top 50 percent of competitors.


Alzheimer's Memory Walk
The UB SoPPS student team of Becca Campbell, P1; Brittany Andrusko, P2; Emily Krecko, P3; Aleem Merani, P3; and Christopher Tanski, P3, raised more than $500 in the 2011 Alzheimer's Memory Walk of Western New York.


Stefanie Wiegand, PharmD/JD Student Receives AACP MedCo $10,000 Scholarship
Congratulations to Stefanie Wiegand, one of four dual-degree students nationally, who was chosen as a MedCo Scholar by the Medco Foundation. Stefanie will receive a $10,000 scholarship as part of the new MedCo Scholars Program administered by the American Association of Colleges of Pharmacy. Read more.


Kerri O'Connor Receives Research Travel Award to Amsterdam
Congratulations to P4 student Kerri O'Connor for receiving a travel award from the European Committee for Treatment and Research in Multiple Sclerosis to attend the Fifth Joint Triennial Congress of the European and American Committee for the Treatment of Multiple Sclerosis in Amsterdam. Her research presentation, titled "Patterns of dietary and herbal supplement use by multiple sclerosis patients," was conducted under the supervision of Murali Ramanathan, associate professor, Pharmaceutical Sciences. It also has been published as a research paper (O'Connor, K; Weinstock-Guttman, B.; Carl, E.; Kilanowski, C.; Zivadinov, R. & Ramanathan, M. Journal of Neurology. 2011 Sept. 6).


Meghan Rowcliffe Publishes Abstract
Congratulations to P4 student Meghan Rowcliffe and her research mentor, Fran Gengo, associate professor, Pharmacy Practice, on the acceptance of their abstract, Pharmacokinetic Postmortem Evaluation Reveals Death from Carbamazepine to be Accidental Rather than Criminal, by the American Academy of Forensic Sciences (AAFS). They also will be presenting a poster at the AAFS's 64th annual meeting.


Halfway Dance and Charity Gala: Saturday, Feb. 11, 2012, 6:30 p.m., Hyatt Regency, Buffalo. Tickets are $60 and discount room reservations are available. Questions: Nick Hopwood, P2 vice president: nhopwood@buffalo.edu.


Ninth Annual Student Scholarship Golf Tournament: Monday, June 11, 2012, Lockport Town and Country Club.

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