2008 July eNotes


University at Buffalo School of Pharmacy and Pharmaceutical Sciences
July 2008
Dean's e-Notes
Welcome to the July SoPPS Dean's e-Notes. Summer months allow our faculty and staff to prepare for the upcoming academic year and our students to take a much needed respite and recharge for the 2008-09 academic year. Orientation and other welcoming activities are being planned for the Class of 2012. Updates on these activities and other beginning-of-semester activities will be the focus of our September eNotes.

Please stay in touch. Forward updates on your personal and professional accomplishments by e-mail to phm-alumni@buffalo.edu. You will hear from us again in July.

With warm regards,
Wayne K. Anderson, Ph.D., professor and dean
Wayne Anderson, Ph.D., professor and dean
Center of Excellence
New York State Center of Excellence in Bioinformatics and Life Sciences
School News
Center for Protein Therapeutics Opens
The School of Pharmacy and Pharmaceutical Sciences is proud to announce the official opening of its Center for Protein Therapeutics at the New York State Center of Excellence in Bioinformatics and Life Sciences. Opening activities included the center's management committee grant review meeting held on June 26 when grant proposals were reviewed for merit and funding. The center's management committee is composed of members of the Department of Pharmaceutical Sciences as well as representatives from industrial partners Rosalin Arends (Pfizer), Sandra Allerheilgen (Lilly), Victor Wroblewski (Lilly), Wolfgang Richter (Roche), Ying Ou (Roche) and Thomayant Prueksaritanont (Merck). More

The grant review meeting approved the following 10 projects for funding:


  • Physiologically based pharmacokinetic (PBPK) modeling of IgG (PI: Joseph Balthasar)
  • Investigation of determinants of IgG distribution in the brain (PI: Joseph Balthasar)
  • PK/PD/PG/DIS models for etanercept interactions with cytokines in a rat model of RA (PI: William Jusko)
  • Investigation of the influence of FcRn recycling on the target-mediated elimination of anti-CEA monoclonal antibodies in mice (PI: Joseph Balthasar)
  • Lymphatic uptake of proteins: use of whole body fluorescence in rodent studies (PI: Marilyn Morris)
  • Ultrasensitive LC/MS quantification of cytokines in biological samples (PI: Jin Quiz)
  • Investigation of the influence of PHC-gamma-R on the elimination of monoclonal antibodies (PI: Joseph Balthasar)
  • Multistage systems analysis of anti-CD20 mob pharmacodynamics (PI: Donald Mager)
  • Interferon-beta indisposition and effects on osteolytic lesions (PI: Donald Mager)
  • FcRn in natalizumab-treated multiple sclerosis patients (PI: Murali Ramanathan)
Image of Chizanga
Annual Pharmacokinetic/Pharmacodynamic Modeling Course
The annual pharmacokinetic/pharmacodynamic modeling course organized by William Jusko, UB Distinguished Professor, and other faculty members of the Department of Pharmaceutical Sciences, was held in May. This internationally recognized course provides state-of-the-art instruction on the concepts and applications of mathematical modeling in the control of drug action. Also providing a lecture was Joga Gobburu, UB alumnus and director of pharmacometrics at the Food and Drug Administration. The recent course attracted 19 enrollees from other countries, primarily in Europe. The interest of the international science community created an opportunity for UB pharmaceutical sciences faculty members Jusko, Joseph Balthasar and Donald Mager to bring the "Buffalo version" of PK/PD modeling to the University of Paris in January 2009. These three UB faculty members will also be providing a course for the FDA in White Oak, Maryland, in August 2008 as a public benefit.
2008 Pharmacy Practice Research Fellows Day
Pharmacy Practice Research Fellows Day was held June 2 at the UB Center for Tomorrow. Eight research fellows participated in this event where their research topics were presented and discussed. Presentation winners were:
  • Jurgen Bulitta, Pharmacometrics/ID Fellow won "Mechanism-based pharmacodynamic modeling of phenotypic tolerance in Pseudmonas aeruginosa for beta-lactams"
  • Sarah McCabe, UB/Novartis Drug Development Fellow, received second-place honors for "Interspecies scaling of ABC123: estimation of human pharmacokinetics in preparation for first in man studies"
  • Damir Begic, UB/Novartis Drug Development Fellow received third-place honors for "Comparative daptomycin and vancomycin activity against staphylococcus aureus hemB mutants expressing the small-colony-variant (SCV) phenotype"
ICHAPRT's New International Trainee
The UB SoPPS International Center for HIV/AIDS Pharmacotherapy Research and Training is hosting Paveena Sonthisombat, an assistant professor with the faculty of pharmaceutical sciences at Naresuan University in Thailand, for a two-month training program with the UB Pharmacotherapy Research Center and ECMC HIV/AIDS Treatment Education Program. Sonthisombat will receive training in therapeutic drug monitoring, medication adherence and resistance testing to assist her teaching duties at the Naresuan University as well as with inpatient and outpatient HIV services at a nearby hospital.
Alice Ceacareanu Joins Pharmacy Practice Faculty
Alice Ceacareanu, who holds Ph.D and Pharm.D degrees, has joined the Department of Pharmacy Practice as an assistant professor. Ceacareanu will focus her activities in the area of oncology and will be conducting research at the New York State Center of Excellence in Bioinformatics and Life Sciences and the Roswell Park Cancer Institute.
Alumni notes
June Felice Johnson '78 received the Hartig Distinguished Professor Award from the Drake University College of Pharmacy and Health Sciences.
Faculty/Staff notes
Joseph Balthasar was promoted to professor of pharmaceutical sciences.

Edward Bednarczyk was inducted into the National Pharmacy Leadership Society (Phi Lambda Sigma) as a faculty member.

Javier Blanco was promoted to associate professor pharmaceutical sciences.

Gayle Brazeau received the State University of New York 2008 Chancellor's Award for Excellence in Faculty Service.

Linda Catanzaro presented "Addressing Adherence, Toxicity, and Side Effect Concerns in ARVNaive Patients" at the International Association of Physicians in AIDS Care (IAPAC) Promoting HAART Adherence Workshop.

Jean Costanzo joined the staff of the Department of Pharmacy Practice as the introductory pharmacy practice experience coordinator. She will be assisting with student experiences in their first three professional years.

Jennifer Hess was elected college delegate, New York State Association for College Admission Counseling (NYSACAC) for the 2008-11 term. Jennifer also received the State University of New York College Admissions Professionals Outstanding Achievement Award for excellence in the design and/or creation of an admissions print or marketing piece.
Karl Fiebelkorn
Karl Fiebelkorn was promoted to clinical associate professor, pharmacy practice and Associate Dean for Student Affairs and Professional Relations. He was also appointed chairman of the New York State Pharmacy Conference and was awarded the W. Bruce Philip Certificate of Commendation by the national Kappa Psi pharmaceutical fraternity.

Gene Morse was invited to serve on the faculty of the 2008 ACCP Research Institute Focused Investigator Training Program and was also invited to participate in the HRSA Office of Pharmacy Affairs Patient Safety and Clinical Pharmacy Collaborative State Leadership and Action meeting.

Oksana Wisniewski, support staff person in the Department of Pharmacy Practice, was inducted into the National Pharmacy Leadership Society (Phi Lambda Sigma) as an honorary member.

Gina Zurick et al published "A Systematic Approach to Identifying Drug-Seeking Patients" in Family Practice Management. 2008 Apr 15(4): A3-5.
Student Notes
Schomburg Fellowship Winners
The school is pleased to announce that 10 P2 students were selected to receive New York State-sponsored Arthur A. Schomburg Fellowships. These fellowships are awarded to historically underrepresented students in graduate programs who possess outstanding academic credentials. Congratulations to these students from the Class of 2011: Rezarta Ajazi, Oluwa Toyin Fabiyi, Jathiyah Lewis, Jackson Maina, Angela Mwaura, Patricia Ng, John Nguyen, Grace Shyh, Vinh Tran, Yu Ching Tse.
Upcoming continuing education programs

Alumni Reunion and Dinner Dance: Saturday, September 27, 2008, Grand Island Holiday Inn Resort and Conference Center.
Questions: phm-alumni@buffalo.edu.
To register (as of 7/28/08).

For additional information, please see our news and events listings at www.pharmacy.buffalo.edu/school_news.shtml.
School of Pharmacy and Pharmaceutical Sciences • Office of External Affairs
716.645.3340 • phm-alumni@buffalo.edu • www.pharmacy.buffalo.edu