May 11-13, 2017
Niagara Falls, NY
A three day PK/PD modeling course that transitions from simple modeling problems using the industry leading Phoenix WinNonlin software into more complex modeling examples using the nonlinear mixed effect modeling program Phoenix NLME. This hybrid course will focus on basic tutorials along with hands-on problem solving using Phoenix WinNonlin and NLME.
Daniel L. Weiner, Ph.D.
Dr. Weiner has extensive drug development experience and has served as an expert consultant to the U.S. Food and Drug Administration (FDA) on pharmacokinetic modeling and bioequivalence assessment. Dr. Weiner is the co-author of Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications’ 4th ed. (2006). He is a codeveloper of PCNonlin, NONLIN84, and WinNonlin and has presented numerous workshops on the statistical evaluation of pharmacokinetic and bioavailability data.
Dr. Weiner is currently an industry consultant and has held previous management positions including Chief Scientific Officer and Senior Vice President at Certara/Pharsight Corporation; Head of Biostatistics, Merrell Dow Pharmaceuticals; Vice President, Statistical Consultants, Inc.; Vice President, Syntex Development Research; Senior Vice President and Principal Scientist, Quintiles; and Senior Vice President and Global Head of Clinical Development at IVAX Research.
|Monday, May 11||Tuesday, May 12||Wednesday, May 13
|08:00-08:30||Continental Breakfast/Registration||08:00-08:30||Continental Breakfast||08:00-08:30||Continental Breakfast|
|08:30-09:15||Introduction||08:30-09:15||Comparing Models||08:30-10:00||Hands-on (transduction)|
|09:15-10:15||Introduction to WinNonlin – Demo||09:15-10:00||Introduction to Hands-on Examples – Part 3||10:00-10:15||Coffee|
|10:15-10:30||Coffee||10:00-10:15||Coffee||10:15-11:15||Combining Several Sources of Data: Nonlinear Mixed Effects|
|10:30-12:00||Introduction to Hands-on Examples – Part 1 (Graphs and NCA)||10:15-12:00||Hands-on (PD Equilibrium Emax Models)||11:15-12:00||Hands-on (Population PK/PD data and TMDD)|
|13:00-14:00||Properties of Parameter Estimates||13:00-15:00||Hands-on (PK/PD Distributional delays)||13:00-15:00||Hands-on (Population PK/PD data and TMDD)|
|14:00-15:00||Error Models||15:00-15:15||Refreshments||15:00-15:15||Wrap up and Closing Remarks|
|15:00-15:15||Refreshments||15:15-17:00||Hands-on (PK/PD Turnover)|
|15:15-16:00||Assessment of Goodness of Fit|
|16:00-17:00||Introduction to Hands-on Examples – Part 2 (Built in PK Models)|
Individual fee is $2,000. Up to five (5) graduate students may enroll at a fee of $1,200 (registered MS and PhD). US Government rate: $1,600. The registration fee includes course documentation and temporary software license. Continental breakfasts, lunches, break-time refreshments, and opening dinner are also included.
Cancellations with a full refund may be made until March 13, 2017. No refund is possible on cancellations received after this date. Substitutions may be made at any time. Please inform course secretary of any substitutions.
The course will be held at:
The Conference and Event Center Niagara Falls
101 Old Falls Street
Niagara Falls, NY 14303, USA
Phone: (716) 278-2100
Fax: (716) 278-0008
The Conference Center is 28 minutes from the Buffalo Niagara International Airport.
Sheraton at the Falls
300 Third Street
Niagara Falls, NY 14303, USA
Phone: (716) 285-3361.
The price is $124/night single and double occupancy (add $10 per person for triple and quadruple occupancy).
Hotel deadline: April 3, 2017
Contact UB course secretary Suzette Mis at (716) 645-4831 or firstname.lastname@example.org if you need assistance.