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> Pharmaceutical Sciences
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What are the Pharmaceutical Sciences?
The Pharmaceutical Sciences...
- combine an integrated
knowledge of chemistry, biology, mathematics and
computer sciences with human anatomy, physiology,
biochemistry, disease and therapeutics to optimize
patient drug therapy!
- focus on the
design, development and rational use of
medications for the treatment and prevention of
disease
- contribute to the drug
development and research process in the development of new
medications
The Pharmaceutical Sciences seek to provide answers to:
- What dosage form or drug delivery system
should be used?
- How much of a dose should be
administered?
- How
frequently should the dose be
administered?
-
Will the medication interact with other
drugs?
-
Should the dose be individualized based on
age, body weight and composition, lifestyle factors, medical
history, other diseases, and gene
expression?
Areas of interest in the Pharmaceutical Sciences include:
- the physical chemistry of pharmaceutical
systems, which is concerned with the development and optimization
of the physical/chemical properties of traditional and novel drug
delivery systems;
- biopharmaceutics, which
encompasses the study of the relationship between the nature and
intensity of biologic effects of drugs and various dosage form
formulation factors;
-
pharmacokinetics and pharmacodynamics, which are the
sciences of the quantitative analyses of drug concentrations and
therapeutic effects, respectively, in the human
body;
-
clinical pharmacokinetics and clinical pharmacodynamics,
which are concerned with the application of pharmacokinetics and
pharmacodynamics to the safe and effective therapeutic management
of individual patients;
-
pharmacogenomics and bioinformatics, which
are new, emerging scientific disciplines concerned with (1) how
an individual's genotype governs his/her drug concentrations and
therapeutic response; and (2) how drugs may alter a person's gene
expression; and
-
pharmacometrics, which is a
new field that fuses pharmacology, computer sciences, mathematics
and statistics to analyze diverse data in large populations of
diverse patients.
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