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MS in Pharmaceutical Sciences - Pharmacometrics Track

Studies in preclinical and clinical pharmacology, pharmacokinetics, pharmacodynamics, and toxicology typically involve collection of various types of experimental data in individuals and groups of biologic preparations, animals, and human subjects. Appropriate methods of analysis of such data requires an understanding of the underlying science and well as use of biostatistics, computational methods, and pharmacokinetic and pharmacodynamic modeling.

Scientists with proficiency in pharmacometrics can assist in the design and analysis of protocols and studies related to drug therapy questions and provide insights into the processes which control the time course of drug concentrations and clinical, pharmacologic and toxicologic responses.

Prerequisites

Calculus (e.g., MTH 141) and computer programming (eg. C++, Fortran, Visual Basic)

Course Requirements

Enrollment in the Pharmaceutical Sciences Department and completion of 30 credits of academic work. It is expected that program completion will be within 1 year.

A. Required Courses (12 credits) F = Fall, S = Spring

B. Recommended Elective Courses (16 credits)

Note

Students with a biological background should emphasize computational types of electives while those with a math/statistics background should take biomedical electives.

C. PHC 616 (1-5) S Research

Completion of a research project under supervision or collaboration with a suitable graduate faculty member in the School . This project must involve data analysis and modeling. A project report in the form of a manuscript must be submitted and, if convenient, presentation of a poster at a suitable forum.

Supervision: One member of the Graduate Faculty of the School of Pharmacy will serve as Supervisor and two other faculty members will serve on the MS Committee.

D. PHC 613, 614 (1,1) F,S. Seminar

Students will be expected to attend the regular weekly departmental seminar.

Note: Students will be required to attend tutorials in use and applications of software such as Adapt II, Kinetica, WinNonMix, NonMem, and perhaps other programs.

E. Examination

A final oral examination will be required at the end of the academic and research program. This will be administered by the student¹s MS Committee in tandem with the presentation and defense of the research project.

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